Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 15/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.48 |
| ▸ | HTR1A | P08908 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | HTR1B | P28222 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10505338 | 0.89 | ADRB3 (0.40) | ADRB3ADRB2ADRB1HTR1ACYP3A4 | |
| SCHEMBL10593570 | 0.87 | ADRB2 (0.47) | ADRB3ADRB2ADRB1HTR1ACYP1A2 | |
| SCHEMBL10593257 | 0.85 | ADRB3 (0.49) | ADRB3ADRB2ADRB1HTR1ACYP1A2 | |
| SCHEMBL10593379 | 0.82 | GRK3 (0.37) | ADRB3ADRB2ADRB1CYP1A2MEN1 | |
| SCHEMBL10593454 | 0.81 | ADRB1 (0.49) | ADRB3ADRB2ADRB1HTR1ACYP1A2 | |
| SCHEMBL10504871 | 0.81 | ADRB3 (0.49) | ADRB3ADRB2ADRB1HTR1ACYP1A2 | |
| SCHEMBL10593380 | 0.81 | ADRB1 (0.42) | ADRB3ADRB2ADRB1HTR1ADRD4 | |
| SCHEMBL10592682 | 0.80 | ADRB1 (0.51) | ADRB3ADRB2ADRB1HTR1AOPRK1 | |
| SCHEMBL10593360 | 0.80 | MEN1 (0.35) | ADRB3ADRB2ADRB1CYP1A2CYP3A4 | |
| SCHEMBL10593229 | 0.80 | KMT2A (0.34) | ADRB3ADRB2ADRB1HTR1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4863949-A | CARDIOVASCULAR DISORDER TREATMENT | BOEHRINGER MANNHEIM GMBH (DE) | 1989-09-05 | — | — | US | disclosed |