Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 10/20 | 0.40 |
| ▸ | EDNRA | P25101 | 10/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.40 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1059489 | 1.00 | EDNRB (0.40) | EDNRBEDNRANR1I2KCNE1KCNQ1 | |
| SCHEMBL22693305 | 0.87 | MAOA (0.35) | EDNRBEDNRANR1I2KCNE1KCNQ1 | |
| SCHEMBL15655487 | 0.78 | MAPK1 (0.33) | MAPK1KCNN4ALDH1A1ALOX15 | |
| SCHEMBL2325083 | 0.78 | TSHR (0.37) | MAPK1KCNN4ALDH1A1ALOX15 | |
| SCHEMBL28058949 | 0.78 | MAPK1 (0.33) | MAPK1KCNN4ALDH1A1ALOX15 | |
| SCHEMBL4268612 | 0.78 | MAPK1 (0.33) | MAPK1KCNN4ALDH1A1ALOX15 | |
| SCHEMBL1059491 | 0.78 | MAPK1 (0.34) | EDNRBEDNRANR1I2KCNE1KCNQ1 | |
| SCHEMBL1059509 | 0.78 | EDNRB (0.42) | EDNRBEDNRAPOLBMAPK1KCNN4 | |
| SCHEMBL1059493 | 0.78 | MAPK1 (0.34) | EDNRBEDNRANR1I2KCNE1KCNQ1 | |
| SCHEMBL1059507 | 0.78 | EDNRB (0.42) | EDNRBEDNRAPOLBMAPK1KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2500088-A2 | Molecular recognition material and production method thereof | Shiseido Co., Ltd. (JP) | 2012-09-19 | — | — | EP | disclosed |
| US-20110021347-A1 | Molecule Recognizing Material And Process For Producing The Molecule Recognizing Material | KEIO UNIVERSITY (JP) | 2011-01-27 | — | — | US | disclosed |
| EP-2198952-A1 | MOLECULE RECOGNIZING MATERIAL AND PROCESS FOR PRODUCING THE MOLECULE RECOGNIZING MATERIAL | Keio University (JP) | 2010-06-23 | — | — | EP | disclosed |