SCHEMBL1059489

SCHEMBL1059489

COC(c1ccccc1)(c1ccccc1)C(c1ccccc1)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
EDNRB P24530 10/20 0.40
EDNRA P25101 10/20 0.40
NR1I2 O75469 1/20 0.40
KCNE1 P15382 1/20 0.40
KCNQ1 P51787 1/20 0.40
POLB P06746 1/20 0.40
MAPK1 P28482 1/20 0.38
CES1 P23141 1/20 0.37
KCNN4 O15554 2/20 0.36
KMT2A Q03164 1/20 0.36
ALDH1A1 P00352 2/20 0.35
ALOX15 P16050 1/20 0.35
THRB P10828 1/20 0.35
GAA P10253 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1059487 1.00 EDNRB (0.40) EDNRBEDNRANR1I2KCNE1KCNQ1
SCHEMBL22693305 0.87 MAOA (0.35) EDNRBEDNRANR1I2KCNE1KCNQ1
SCHEMBL15655487 0.78 MAPK1 (0.33) MAPK1KCNN4ALDH1A1ALOX15
SCHEMBL2325083 0.78 TSHR (0.37) MAPK1KCNN4ALDH1A1ALOX15
SCHEMBL28058949 0.78 MAPK1 (0.33) MAPK1KCNN4ALDH1A1ALOX15
SCHEMBL4268612 0.78 MAPK1 (0.33) MAPK1KCNN4ALDH1A1ALOX15
SCHEMBL1059491 0.78 MAPK1 (0.34) EDNRBEDNRANR1I2KCNE1KCNQ1
SCHEMBL1059509 0.78 EDNRB (0.42) EDNRBEDNRAPOLBMAPK1KCNN4
SCHEMBL1059493 0.78 MAPK1 (0.34) EDNRBEDNRANR1I2KCNE1KCNQ1
SCHEMBL1059507 0.78 EDNRB (0.42) EDNRBEDNRAPOLBMAPK1KCNN4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115746182-B Catalyst for olefin polymerization and olefin polymerization method 中国石油化工股份有限公司 2024-03-26 CN claimed
CN-115746177-B Catalyst for olefin polymerization and olefin polymerization method 中国石油化工股份有限公司 2024-03-26 CN claimed
CN-115746182-A Catalyst for olefin polymerization and olefin polymerization method 中国石油化工股份有限公司 2023-03-07 CN claimed
US-6967229-B2 Carbon-carbon initiators for use in golf balls ACUSHNET COMPANY (US) 2005-11-22 US claimed
US-20050009992-A1 Carbon-carbon initiators for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-01-13 US claimed
US-3944511-A Chemically modified polymers OWENS-ILLINOIS, INC. (US) 1976-03-16 US claimed
CN-115746182-B Catalyst for olefin polymerization and olefin polymerization method 中国石油化工股份有限公司 2024-03-26 CN disclosed
CN-115746177-B Catalyst for olefin polymerization and olefin polymerization method 中国石油化工股份有限公司 2024-03-26 CN disclosed
US-20170165940-A1 LAMINATE AND METHOD OF PRODUCTION OF BUILT-UP BOARD ZEON CORPORATION (JP) 2017-06-15 US disclosed
EP-2927302-A1 FLAME RETARDANT COMPOSITION BASED ON SUBSTITUTED DI-, TRI- AND TETRA ARYLETHANE COMPOUNDS BASF SE (DE) 2015-10-07 EP disclosed
EP-2927302-A1 FLAME RETARDANT COMPOSITION BASED ON SUBSTITUTED DI-, TRI- AND TETRA ARYLETHANE COMPOUNDS BASF SE (DE) 2015-10-07 EP disclosed
US-9056227-B2 Golf ball comprising a core having a shallow hardness gradient ACUSHNET COMPANY (US) 2015-06-16 US disclosed
US-8968117-B2 Dual-core comprising zero gradient center and positive gradient outer core layer ACUSHNET COMPANY (US) 2015-03-03 US disclosed
EP-1188807-A2 Chemical mechanical polishing stopper film, process for producing the same, and method of chemical mechanical polishing JSR Corporation (JP) 2002-03-20 EP disclosed
US-6323300-B1 ELECTRICAL CHARACTERISTICS SUCH AS A LOW DIELECTRIC CONSTANT, HEAT RESISTANCE, FILM-FORMING PROPERTIES, WATER ABSORPTION PROPERTIES AND ADHESION TO OTHER MATERIALS, FOR ELECTRONIC PARTS ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 2001-11-27 US disclosed
US-20010012870-A1 Composition for film formation and insulating film JSR CORPORATION (JP) 2001-08-09 US disclosed
EP-1122746-A1 Composition for film formation and insulating film JSR Corporation (JP) 2001-08-08 EP disclosed
EP-1099719-A1 Diyne-containing (co) polymer, processes for producing the same, and cured film JSR Corporation (JP) 2001-05-16 EP disclosed
EP-0940419-A1 AROMATIC COPOLYMER AND COMPOSITION CONTAINING THE SAME Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1999-09-08 EP disclosed
US-3944511-A Chemically modified polymers OWENS-ILLINOIS, INC. (US) 1976-03-16 US disclosed