SCHEMBL10595010

SCHEMBL10595010

O=C(OCc1ccccc1)Oc1cccc2ccccc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 4/20 0.54
KMT2A Q03164 3/20 0.54
MRGPRX4 Q96LA9 1/20 0.52
ALDH1A1 P00352 7/20 0.51
KDM4E B2RXH2 2/20 0.51
HPGD P15428 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
GAA P10253 2/20 0.50
MAPK1 P28482 2/20 0.50
PGR P06401 1/20 0.50
PTGS1 P23219 1/20 0.50
MEN1 O00255 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
RAB9A P51151 1/20 0.49
MAPT P10636 1/20 0.48
HTT P42858 1/20 0.48
GFER P55789 1/20 0.48
CASP1 P29466 1/20 0.46
FABP3 P05413 5/20 0.46
FABP7 O15540 4/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22882716 0.85 ALDH1A1 (0.57) HSD17B10KMT2AALDH1A1TDP1MAPK1
SCHEMBL6708065 0.84 CYP1A2 (0.51) HSD17B10KMT2AMRGPRX4ALDH1A1KDM4E
SCHEMBL27062377 0.82 NCEH1 (0.46) HSD17B10KMT2AALDH1A1TDP1MAPK1
SCHEMBL26548507 0.82 NCEH1 (0.56) HSD17B10KMT2AALDH1A1TDP1GAA
SCHEMBL37865 0.81 ALDH1A1 (0.65) HSD17B10KMT2AALDH1A1KDM4EHPGD
SCHEMBL29901836 0.81 ALDH1A1 (0.65) HSD17B10KMT2AALDH1A1KDM4EHPGD
SCHEMBL4069381 0.81 ALDH1A1 (0.57) HSD17B10KMT2AALDH1A1KDM4EHPGD
SCHEMBL6891715 0.81 ALDH1A1 (0.53) HSD17B10KMT2AALDH1A1KDM4EHPGD
SCHEMBL31602199 0.80 HSD17B10 (0.47) HSD17B10KMT2AMRGPRX4ALDH1A1KDM4E
SCHEMBL27062379 0.80 NCEH1 (0.60) HSD17B10KMT2AALDH1A1MEN1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170050855-A1 WATER, BUBBLE COLLAPSE AND SYNGAS SPECIES IN THE SYNTHESIS OF GRAPHENE AND ITS DERIVATIVES PEERLESS WORLDWIDE, LLC (US) 2017-02-23 US claimed
US-9932238-B2 Graphene and graphene oxide nano-environments for chemical reactions and atomic reformations PEERLESS WORLDWIDE, LLC (US) 2018-04-03 US disclosed
US-20150307971-A1 GRAPHENE AND GRAPHENE OXIDE NANO-ENVIRONMENTS FOR CHEMICAL REACTIONS AND ATOMIC REFORMATIONS PEERLESS WORLDWIDE, LLC (US) 2015-10-29 US disclosed
US-9023308-B2 Facile synthesis of graphene, graphene derivatives and abrasive nanoparticles and their various uses, including as tribologically-beneficial lubricant additives PEERLESS WORLDWIDE, LLC (US) 2015-05-05 US disclosed
US-8865113-B2 Facile synthesis of graphene, graphene derivatives and abrasive nanoparticles and their various uses, including as tribologically-beneficial lubricant additives PEERLESS WORLDWIDE, LLC (US) 2014-10-21 US disclosed
US-20140227211-A1 FACILE SYNTHESIS OF GRAPHENE, GRAPHENE DERIVATIVES AND ABRASIVE NANOPARTICLES AND THEIR VARIOUS USES, INCLUDING AS TRIBOLOGICALLY-BENEFICIAL LUBRICANT ADDITIVES PEERLESS WORLDWIDE, LLC (US) 2014-08-14 US disclosed
US-20140134092-A1 FACILE SYNTHESIS OF GRAPHENE, GRAPHENE DERIVATIVES AND ABRASIVE NANOPARTICLES AND THEIR VARIOUS USES, INCLUDING AS TRIBOLOGICALLY-BENEFICIAL LUBRICANT ADDITIVES SHANKMAN RICHARD S (US) 2014-05-15 US disclosed
EP-2686271-A1 FACILE SYNTHESIS OF GRAPHENE, GRAPHENE DERIVATIVES AND ABRASIVE NANOPARTICLES AND THEIR VARIOUS USES, INCLUDING AS TRIBOLOGICALLY-BENEFICIAL LUBRICANT ADDITIVES Peerless Worldwide, LLC (US) 2014-01-22 EP disclosed
CN-103534205-A Facile synthesis of graphene, graphene derivatives and abrasive nanoparticles, and their various uses, including as tribologically-beneficial lubricant additives PEERLESS WORLDWIDE LLC 2014-01-22 CN disclosed
WO-2012125854-A1 FACILE SYNTHESIS OF GRAPHENE, GRAPHENE DERIVATIVES AND ABRASIVE NANOPARTICLES AND THEIR VARIOUS USES, INCLUDING AS TRIBOLOGICALLY-BENEFICIAL LUBRICANT ADDITIVES PEERLESS WORLDWIDE, LLC (US) 2012-09-20 WO disclosed
US-4833118-A COLOR DEVELOPERS, SUBBING LAYERS, AROMATIC ESTERS OR CARBONATES FUJI PHOTO FILM CO., LTD. (JP) 1989-05-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140227211-A1 FACILE SYNTHESIS OF GRAPHENE, GRAPHENE DERIVATIVES AND ABRASIVE NANOPARTICLES AND THEIR VARIOUS USES, INCLUDING AS TRIBOLOGICALLY-BENEFICIAL LUBRICANT ADDITIVES GRN, CCNO, TELO2 HSD17B10 4321/4885KMT2A 2911/4885MRGPRX4 3670/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.