Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | PREP | P48147 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10595318 | 1.00 | RAB9A (0.47) | RAB9ACHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL27922142 | 0.88 | RAB9A (0.44) | RAB9ASMN1; SMN2ALDH1A1HSD17B10PREP | |
| SCHEMBL28836255 | 0.87 | RAB9A (0.61) | RAB9ASMN1; SMN2ALDH1A1HSD17B10LMNA | |
| SCHEMBL7367598 | 0.87 | RAB9A (0.61) | RAB9ASMN1; SMN2ALDH1A1HSD17B10LMNA | |
| SCHEMBL3065176 | 0.83 | RAB9A (0.53) | RAB9ASMN1; SMN2ALDH1A1FKBP1APREP | |
| SCHEMBL7946008 | 0.83 | RAB9A (0.53) | RAB9ASMN1; SMN2ALDH1A1FKBP1APREP | |
| SCHEMBL7948659 | 0.83 | RAB9A (0.53) | RAB9ASMN1; SMN2ALDH1A1FKBP1APREP | |
| SCHEMBL10595311 | 0.78 | HSD17B10 (0.40) | RAB9ASMN1; SMN2ALDH1A1HSD17B10LMNA | |
| SCHEMBL14908297 | 0.78 | RAB9A (0.44) | RAB9ACHRM1SMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL5701849 | 0.77 | RAB9A (0.49) | RAB9ACHRM2CHRM4CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0168950-B1 | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BECKMAN CORPORATION (US) | 1989-01-11 | — | — | EP | disclosed |
| EP-0168950-A1 | Leukotriene antagonists | SMITHKLINE BECKMAN CORPORATION (US) | 1986-01-22 | — | — | EP | disclosed |