Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL9807679 | 0.77 | MAPT (0.51) | MAPTALDH1A1 | |
| SCHEMBL10597090 | 0.75 | CYP1A2 (0.57) | POLBTSHRCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL10827796 | 0.74 | ALDH1A1 (0.52) | POLBTSHRMAPTHPGDNPC1 | |
| SCHEMBL27866 | 0.73 | CYP2D6 (0.80) | POLBTSHRCYP1A2CYP2D6CYP2C9 | |
| Iodide SCHEMBL30583028 | 0.72 | CYP2D6 (0.77) | POLBTSHRCYP1A2CYP2D6CYP2C9 | |
| Bromide SCHEMBL21847280 | 0.72 | CYP2D6 (0.77) | POLBTSHRCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL28383085 | 0.72 | CYP2D6 (0.77) | POLBTSHRCYP1A2CYP2D6CYP2C9 | |
| Ammonia Solution, Strong SCHEMBL22534204 | 0.72 | CYP2D6 (0.77) | POLBTSHRCYP1A2CYP2D6CYP2C9 | |
| Hydrogen Sulfide SCHEMBL10338701 | 0.72 | CYP2D6 (0.77) | POLBTSHRCYP1A2CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL3219100 | 0.72 | CYP2D6 (0.77) | POLBTSHRCYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126713-B1 | CYCLOHEXANEDIONE-CARBOXYLIC-ACID DERIVATIVES HAVING A HERBICIDAL AND PLANT GROWTH REGULATING ACTIVITY | CIBA-GEIGY AG (CH) | 1989-01-18 | — | — | EP | disclosed |
| EP-0126713-A2 | Cyclohexanedione-carboxylic-acid derivatives having a herbicidal and plant growth regulating activity | CIBA-GEIGY AG (CH) | 1984-11-28 | — | — | EP | disclosed |