Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 2/20 | 0.31 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.30 |
| ▸ | ACE | P12821 | 1/20 | 0.30 |
| ▸ | CPA1 | P15085 | 1/20 | 0.30 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL541433 | 0.80 | TSHR (0.39) | TSHRALDH1A1MAPTMMEFAAH | |
| SCHEMBL541431 | 0.80 | TSHR (0.39) | TSHRALDH1A1MAPTMMEFAAH | |
| SCHEMBL8990457 | 0.78 | TSHR (0.38) | TSHRALDH1A1MAPTMMEFAAH | |
| SCHEMBL8990461 | 0.78 | TSHR (0.38) | TSHRALDH1A1MAPTMMEFAAH | |
| SCHEMBL88209 | 0.77 | CYP1A2 (0.44) | TSHRALDH1A1THRBHSD17B10BBOX1 | |
| SCHEMBL3713828 | 0.77 | CYP1A2 (0.44) | TSHRALDH1A1THRBHSD17B10BBOX1 | |
| SCHEMBL14037307 | 0.76 | TSHR (0.40) | TSHRALDH1A1THRBHSD17B10MME | |
| SCHEMBL20677353 | 0.76 | TSHR (0.40) | TSHRALDH1A1THRBHSD17B10MME | |
| SCHEMBL29138980 | 0.76 | ALDH1A1 (0.40) | TSHRALDH1A1THRBHSD17B10MAPT | |
| SCHEMBL1597808 | 0.76 | TSHR (0.36) | TSHRALDH1A1BBOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE32952-E | ONE-POT; REACTING KETONE, AMMONIUM SALT, CYANIDE SALT; ACRYLOYLATION, HYDROLYSIS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-06-13 | — | — | US | claimed |
| EP-0246849-A1 | Method of preparing N-acryloyl-alpha-amino acids | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-11-25 | — | — | EP | claimed |
| US-4694103-A | Method of preparing N-acryloyl-α-amino acids | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-09-15 | — | — | US | claimed |
| US-RE32952-E | ONE-POT; REACTING KETONE, AMMONIUM SALT, CYANIDE SALT; ACRYLOYLATION, HYDROLYSIS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-06-13 | — | — | US | disclosed |
| EP-0246849-A1 | Method of preparing N-acryloyl-alpha-amino acids | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-11-25 | — | — | EP | disclosed |
| US-4694103-A | Method of preparing N-acryloyl-α-amino acids | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-09-15 | — | — | US | disclosed |