Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | CPA1 | P15085 | 1/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990457 | 1.00 | TSHR (0.38) | TSHRALDH1A1MMEACECPA1 | |
| SCHEMBL541433 | 0.98 | TSHR (0.39) | TSHRALDH1A1MMEACECPA1 | |
| SCHEMBL541431 | 0.98 | TSHR (0.39) | TSHRALDH1A1MMEACECPA1 | |
| SCHEMBL10596065 | 0.78 | TSHR (0.38) | TSHRALDH1A1MMEACECPA1 | |
| SCHEMBL1700840 | 0.73 | ALDH1A1 (0.43) | ALDH1A1MMEACECPA1ACE2 | |
| SCHEMBL2132525 | 0.73 | ALDH1A1 (0.43) | ALDH1A1MMEACECPA1ACE2 | |
| SCHEMBL2805307 | 0.73 | ALDH1A1 (0.43) | ALDH1A1MMEACECPA1ACE2 | |
| SCHEMBL253527 | 0.72 | — | — | |
| SCHEMBL725364 | 0.72 | — | — | |
| SCHEMBL905194 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0392735-B1 | Polymeric supports | MINNESOTA MINING & MFG (US) | 1996-07-17 | — | — | EP | disclosed |
| US-5403902-A | Addition polymerization of water soluble monomers, at least one alkenyl azlactone and crosslinker; useful as complexing agents, supports of chromatography, enzymatic components | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-04-04 | — | — | US | disclosed |
| US-5336742-A | Azlactone-functional polymer supports, e.g. beads; complexing agents, catalysts and biological reagent for proteins and enzymes | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-08-09 | — | — | US | disclosed |
| US-5292840-A | Acrylic amide adducts | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-03-08 | — | — | US | disclosed |
| EP-0354909-B1 | VARIABLE CROSSLINKED POLYMERIC SUPPORTS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-01-02 | — | — | EP | disclosed |
| EP-0392735-A2 | Polymeric supports | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-10-17 | — | — | EP | disclosed |
| US-4871824-A | AZLACTONE FUNCTIONAL POLYMER BEADS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-10-03 | — | — | US | disclosed |
| US-4737560-A | AZLACTONE FUNCTIONAL | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1988-04-12 | — | — | US | disclosed |