Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | GRM1 | Q13255 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | RGS12 | O14924 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3620858 | 0.78 | MEN1 (0.56) | MEN1KMT2ACYP1A2CYP3A4GRM1 | |
| SCHEMBL19426166 | 0.78 | KMT2A (0.40) | MEN1KMT2ACYP1A2CYP3A4GRM1 | |
| SCHEMBL10595878 | 0.78 | KDM6B (0.39) | MEN1KMT2ACYP1A2CYP3A4HPGD | |
| SCHEMBL10595884 | 0.78 | KDM6B (0.39) | MEN1KMT2ACYP1A2CYP3A4HPGD | |
| SCHEMBL8622029 | 0.77 | MEN1 (0.54) | MEN1KMT2ACYP1A2CYP3A4GRM1 | |
| SCHEMBL30938556 | 0.77 | MEN1 (1.00) | MEN1KMT2ACYP1A2CYP3A4GRM1 | |
| SCHEMBL29370768 | 0.77 | MEN1 (1.00) | MEN1KMT2ACYP1A2CYP3A4GRM1 | |
| SCHEMBL12648575 | 0.77 | MEN1 (1.00) | MEN1KMT2ACYP1A2CYP3A4GRM1 | |
| Hydrochloric Acid SCHEMBL8617929 | 0.76 | MEN1 (0.53) | MEN1KMT2ACYP1A2CYP3A4GRM1 | |
| SCHEMBL9351094 | 0.73 | CYP3A4 (0.35) | MEN1KMT2ACYP1A2CYP3A4GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0131174-B1 | SUBSTITUTED PHENYLGLYCINE DERIVATIVES OF BETA-LACTAM ANTIBIOTICS | BEECHAM GROUP PLC (GB) | 1989-09-13 | — | — | EP | disclosed |
| US-4684639-A | Antibacterial penicillins and cephalosporins | BEECHAM GROUP (GB) | 1987-08-04 | — | — | US | disclosed |
| EP-0131174-A1 | Substituted phenylglycine derivatives of beta-lactam antibiotics | BEECHAM GROUP PLC (GB) | 1985-01-16 | — | — | EP | disclosed |