Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 6/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.46 |
| ▸ | GRM1 | Q13255 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8617929 | 0.98 | MEN1 (0.53) | MEN1KMT2ACYP1A2CYP3A4CA1 | |
| SCHEMBL6305532 | 0.85 | MEN1 (0.42) | MEN1KMT2ACYP1A2CYP3A4CA1 | |
| SCHEMBL8615977 | 0.81 | MEN1 (0.68) | MEN1KMT2ACYP1A2CYP3A4CA1 | |
| SCHEMBL25362682 | 0.81 | MEN1 (0.68) | MEN1KMT2ACYP1A2CYP3A4CA1 | |
| SCHEMBL3745804 | 0.79 | CA1 (0.50) | MEN1KMT2ACYP1A2CYP3A4CA1 | |
| SCHEMBL3745809 | 0.79 | CA1 (0.50) | MEN1KMT2ACYP1A2CYP3A4CA1 | |
| SCHEMBL17774725 | 0.79 | KDM4E (0.50) | MEN1KMT2ACYP1A2CYP3A4CA1 | |
| SCHEMBL3620858 | 0.79 | MEN1 (0.56) | MEN1KMT2ACYP1A2CYP3A4GRM1 | |
| SCHEMBL11791007 | 0.78 | GRM1 (0.51) | MEN1KMT2ACYP1A2CYP3A4HPGD | |
| SCHEMBL6591473 | 0.78 | PTGS2 (0.57) | MEN1KMT2ACYP1A2CYP3A4CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839799-A1 | 2-HYDROXYPHENYLALKYLAMINE DERIVATIVES AND MAILLARD REACTION INHIBITORS | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-3993666-A | Coumaranedione-3-monoximes | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-23 | — | — | US | disclosed |
| US-3993665-A | 3-Amidocoumaranones | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-23 | — | — | US | disclosed |