Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 7/20 | 0.57 |
| ▸ | RAB9A | P51151 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8616834 | 0.78 | KDM4E (0.59) | KMT2AKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10596825 | 0.77 | SMN1; SMN2 (0.63) | KDM4ENPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL3077089 | 0.76 | KDM4E (0.74) | KDM4ENPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL11253679 | 0.74 | ACHE (0.67) | KMT2ANPC1RAB9ASMN1; SMN2TSHR | |
| Hydrochloric Acid SCHEMBL31169755 | 0.74 | KDM4E (0.72) | KDM4ENPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL4578939 | 0.74 | KDM4E (0.77) | KMT2AKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6127192 | 0.74 | KDM4E (0.89) | KDM4ENPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL4578943 | 0.74 | KDM4E (0.77) | KMT2AKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10595285 | 0.73 | NPC1 (0.64) | KMT2ANPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL4045277 | 0.73 | KDM4E (0.81) | KMT2AKDM4ENPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4560679-A | Organosilicon compounds and antitumor agents containing the compound as effective component | SANWA KAGAKU KENKYUSHO CO. LTD. (JP) | 1985-12-24 | — | — | US | claimed |
| EP-0109195-B1 | ANTITUMOR ORGANOSILICON COMPOUNDS AND THEIR PREPARATION | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1989-01-11 | — | — | EP | disclosed |
| US-4560679-A | Organosilicon compounds and antitumor agents containing the compound as effective component | SANWA KAGAKU KENKYUSHO CO. LTD. (JP) | 1985-12-24 | — | — | US | disclosed |
| EP-0109195-A2 | Antitumor organosilicon compounds and their preparation | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1984-05-23 | — | — | EP | disclosed |