SCHEMBL8942933

SCHEMBL8942933

O=S(=O)(O)C[CH]CCCS(=O)(=O)O

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.44
PTGS1 P23219 1/20 0.36
PDE4A P27815 1/20 0.36
LMNA P02545 1/20 0.36
SLC6A6 P31641 1/20 0.36
CYP2C19 P33261 1/20 0.36
BLM P54132 1/20 0.36
EPHX2 P34913 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28065626 0.93 APP (0.42) APPPTGS1PDE4ALMNASLC6A6
SCHEMBL10596261 0.87 APP (0.50) APPPTGS1PDE4ALMNASLC6A6
SCHEMBL5738161 0.84 PTGS1 (0.39) APPPTGS1PDE4ALMNASLC6A6
SCHEMBL471961 0.80
SCHEMBL4279355 0.78 TSHR (0.40) LMNAEPHX2
SCHEMBL9683215 0.78 APP (0.42) APPPTGS1PDE4ALMNASLC6A6
SCHEMBL16143805 0.78 APP (0.42) APPPTGS1PDE4ALMNASLC6A6
SCHEMBL16446001 0.76 EPHX2 (0.42) APPPTGS1PDE4ALMNASLC6A6
SCHEMBL4266908 0.76 EPHX2 (0.42) EPHX2
SCHEMBL7521234 0.75 APP (0.44) APPPTGS1PDE4ALMNASLC6A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5491057-A FREE FROM FLUCTUATION OF SENSITIVITY UNDER SPONTANEOUS STORAGE FUJI PHOTO FILM CO., LTD. (JP) 1996-02-13 US disclosed