Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | VNN1 | O95497 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22557052 | 0.83 | VNN1 (0.43) | VNN1 | |
| SCHEMBL20646737 | 0.83 | — | — | |
| SCHEMBL1659915 | 0.81 | VNN1 (0.45) | VNN1 | |
| Hydrochloric Acid SCHEMBL22557478 | 0.81 | VNN1 (0.42) | VNN1 | |
| SCHEMBL976560 | 0.81 | PTPN1 (0.61) | GSK3BPTPN1 | |
| SCHEMBL15568708 | 0.81 | GSK3B (0.60) | GSK3BPTPN1 | |
| SCHEMBL19707524 | 0.79 | GSK3B (0.58) | GSK3BPTPN1VNN1 | |
| SCHEMBL19707542 | 0.79 | GSK3B (0.58) | GSK3BPTPN1 | |
| SCHEMBL505097 | 0.78 | HCAR1 (0.53) | — | |
| Hydrochloric Acid SCHEMBL6524503 | 0.77 | HCAR1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0195396-B1 | 5-FLUOROBENZONITRILE DERIVATIVES AND PHARMACOLOGICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF FOR INCREASING THE LEAN MEAT TO FAT RATIO, AND/OR ENHANCING THE GROWTH RATE OF WARM-BLOODED ANIMALS | AMERICAN CYANAMID COMPANY (US) | 1989-03-01 | — | — | EP | claimed |
| EP-0195396-A1 | 5-Fluorobenzonitrile derivatives and pharmacologically acceptable acid addition salts thereof for increasing the lean meat to fat ratio, and/or enhancing the growth rate of warm-blooded animals | AMERICAN CYANAMID COMPANY (US) | 1986-09-24 | — | — | EP | claimed |
| WO-2020212350-A1 | SUBSTITUTED CYANOPYRROLIDINES WITH ACTIVITY AS USP30 INHIBITORS | MISSION THERAPEUTICS LIMITED (GB) | 2020-10-22 | — | — | WO | disclosed |
| EP-0195396-B1 | 5-FLUOROBENZONITRILE DERIVATIVES AND PHARMACOLOGICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF FOR INCREASING THE LEAN MEAT TO FAT RATIO, AND/OR ENHANCING THE GROWTH RATE OF WARM-BLOODED ANIMALS | AMERICAN CYANAMID COMPANY (US) | 1989-03-01 | — | — | EP | disclosed |
| US-4614746-A | 5-fluorobenzonitrile derivatives for increasing the lean meat to fat ratio and/or enhancing the growth rate of warm-blooded animals | AMERICAN CYANAMID COMPANY (US) | 1986-09-30 | — | — | US | disclosed |
| EP-0195396-A1 | 5-Fluorobenzonitrile derivatives and pharmacologically acceptable acid addition salts thereof for increasing the lean meat to fat ratio, and/or enhancing the growth rate of warm-blooded animals | AMERICAN CYANAMID COMPANY (US) | 1986-09-24 | — | — | EP | disclosed |