Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.67 |
| ▸ | RAB9A | P51151 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18375043 | 0.85 | NPC1 (0.59) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL30893054 | 0.85 | NPC1 (0.50) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL7574172 | 0.85 | NPC1 (0.50) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL29813370 | 0.85 | NPC1 (0.54) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL108807 | 0.85 | NPC1 (0.54) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL9567799 | 0.85 | NPC1 (0.50) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL29708 | 0.84 | NPC1 (0.49) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL29350736 | 0.84 | NPC1 (0.49) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL9408718 | 0.82 | NPC1 (0.48) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL6929698 | 0.82 | NPC1 (0.48) | NPC1RAB9ALMNAPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0132402-B1 | METHOD FOR IMPROVING LIGHT-RESISTANCE OF AROMATIC POLYAMIDE FIBERS | TEIJIN LIMITED (JP) | 1989-04-19 | — | — | EP | disclosed |
| US-4631066-A | HEAT TREATMENT WITH UREA, THIOUREA MIXTURE | TEIJIN LIMITED (JP) | 1986-12-23 | — | — | US | disclosed |
| EP-0132402-A2 | Method for improving light-resistance of aromatic polyamide fibers | TEIJIN LIMITED (JP) | 1985-01-30 | — | — | EP | disclosed |