Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30893054 | 1.00 | NPC1 (0.50) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL7574172 | 0.88 | NPC1 (0.50) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL29813370 | 0.88 | NPC1 (0.54) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL108807 | 0.88 | NPC1 (0.54) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL29350736 | 0.86 | NPC1 (0.49) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL29708 | 0.86 | NPC1 (0.49) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL10596458 | 0.85 | NPC1 (0.67) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL9408718 | 0.85 | NPC1 (0.48) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL6929698 | 0.85 | NPC1 (0.48) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL18375140 | 0.84 | NPC1 (0.45) | NPC1RAB9ALMNAPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118043298-A | (Hetero) aryl-substituted bisphenol compound and thermoplastic resin | 罗伊特化学仪器制造公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-115968390-A | Coating liquid for forming pressure measurement layer, method for producing pressure measurement layer, and non-planar part-containing article with pressure measurement layer | 富士胶片株式会社 | 2023-04-14 | — | — | CN | disclosed |
| EP-0570992-A1 | Powder coatings | NIPPON PAINT CO., LTD. (JP) | 1993-11-24 | — | — | EP | disclosed |
| US-5034432-A | Thermosetting or thermoplastic resins for powder coatings | NIPPON PAINT CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |