Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL105823 | 0.85 | NPC1 (0.43) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL108807 | 0.85 | NPC1 (0.54) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL29813370 | 0.85 | NPC1 (0.54) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL30893054 | 0.85 | NPC1 (0.50) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL9567799 | 0.85 | NPC1 (0.50) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL7574172 | 0.85 | NPC1 (0.50) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL29708 | 0.84 | NPC1 (0.49) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL29350736 | 0.84 | NPC1 (0.49) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL9408718 | 0.82 | NPC1 (0.48) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL10596458 | 0.82 | NPC1 (0.67) | NPC1RAB9ALMNAPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944624-B1 | INSOLUBLE S-TRIAZINE DERIVATIVES AND THEIR USE AS UV FILTERS | OREAL (FR) | 2003-11-05 | — | — | EP | disclosed |
| CN-1123572-C | Insoluble s-triazine derivatives, process for their preparation, compositions containing them and their use | OREAL (FR) | 2003-10-08 | — | — | CN | disclosed |
| US-6517742-B1 | 2-(butyl 4'-ylaminobenzoate)-4,6-bis((1,3,3,3-tetramethyl-1 -((trimethylsilyl)oxy)disiloxanyl)propyl-3-ylamino)-s-triazine; s-triazine derivatives substituted by at least one silicone group; from cyanuric chloride | L'OREAL (FR) | 2003-02-11 | — | — | US | disclosed |
| US-6361764-B2 | ULTRAVIOLET LIGHT SCREENING AGENTS; COSMETICS | SOCIETE L'OREAL S.A. (FR) | 2002-03-26 | — | — | US | disclosed |
| US-20020010179-A1 | Novel insoluble S-triazine derivatives, process for their preparation, compositions containing them and uses thereof | RICHARD HERVE (FR) | 2002-01-24 | — | — | US | disclosed |
| CN-1240446-A | Insoluble s-triazine derivatives and their use as UV absorbers | OREAL (FR) | 2000-01-05 | — | — | CN | disclosed |
| EP-0944624-A1 | INSOLUBLE S-TRIAZINE DERIVATIVES AND THEIR USE AS UV FILTERS | L'OREAL (FR) | 1999-09-29 | — | — | EP | disclosed |
| EP-0841341-B1 | Sunscreen agents, and cosmetic compositions containing them | OREAL (FR) | 1999-04-07 | — | — | EP | disclosed |
| WO-1998025922-A1 | INSOLUBLE S-TRIAZINE DERIVATIVES AND THEIR USE AS UV FILTERS | L'OREAL (FR) | 1998-06-18 | — | — | WO | disclosed |
| EP-0841341-A1 | Sunscreen agents, and cosmetic compositions containing them | L'OREAL (FR) | 1998-05-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020010179-A1 | Novel insoluble S-triazine derivatives, process for their preparation, compositions containing them and uses thereof | TST, TYR, TPST2 | NPC1 3874/4885RAB9A 4784/4885LMNA 2677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.