SCHEMBL10597153

SCHEMBL10597153

CCOC(=O)C(C)(O)OS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.45
ALDH1A1 P00352 5/20 0.45
MEN1 O00255 2/20 0.45
MAPT P10636 3/20 0.44
NPSR1 Q6W5P4 2/20 0.44
GAA P10253 1/20 0.44
LMNA P02545 6/20 0.42
RECQL P46063 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TSHR P16473 2/20 0.41
KDM4E B2RXH2 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ABCB11 O95342 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
HTR2A P28223 1/20 0.40
PMP22 Q01453 1/20 0.40
PPARA Q07869 1/20 0.40
THRB P10828 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10598838 0.88 CYP1A2 (0.55) KMT2AALDH1A1MEN1MAPTNPSR1
SCHEMBL10598610 0.88 HSD11B1 (0.47) KMT2AALDH1A1MEN1MAPTNPSR1
SCHEMBL20925382 0.86 KMT2A (0.46) KMT2AALDH1A1MEN1MAPTNPSR1
SCHEMBL20597894 0.82 KMT2A (0.43) KMT2AALDH1A1MEN1MAPTNPSR1
SCHEMBL10602209 0.81 MEN1 (0.46) KMT2AALDH1A1MEN1NPSR1GAA
Potassium Ion SCHEMBL10597702 0.80 KMT2A (0.45) KMT2AALDH1A1MEN1GAALMNA
SCHEMBL10844232 0.80 KMT2A (0.45) KMT2AALDH1A1MEN1GAALMNA
SCHEMBL10597710 0.80 MEN1 (0.45) KMT2AALDH1A1MEN1NPSR1GAA
SCHEMBL10598898 0.80 KMT2A (0.45) KMT2AALDH1A1MEN1GAALMNA
SCHEMBL28217312 0.78 ALDH1A1 (0.47) KMT2AALDH1A1MEN1MAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-61109753-A None JP disclosed
EP-0180126-B1 PROCESS FOR PREPARING 2-(4-HYDROXYPHENOXY)ALKANOIC ACID COMPOUNDS NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1989-01-18 EP disclosed
US-4665212-A Process for preparing 2-(4-hydroxyphenoxy) alkanoic acid compounds NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1987-05-12 US disclosed
JP-S61109753-A PREPARATION OF 2-(4-HYDROXYPHENOXY)ALKANOIC ACID NISSAN CHEM IND LTD 1986-05-28 JP disclosed
EP-0180126-A2 Process for preparing 2-(4-hydroxyphenoxy)alkanoic acid compounds NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1986-05-07 EP disclosed