Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | GDA | Q9Y2T3 | 2/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20867 | 0.80 | ATAD2 (0.53) | PNPDPP4GDAPDPK1ATAD2 | |
| Water SCHEMBL27738785 | 0.79 | ADORA2A (0.54) | PNPDPP4GDAPDPK1ATAD2 | |
| Hydrochloric Acid SCHEMBL27339406 | 0.79 | ATAD2 (0.51) | PNPDPP4GDAPDPK1ATAD2 | |
| SCHEMBL2385672 | 0.78 | PNP (0.44) | PNPDPP4GDAPDPK1MAP3K5 | |
| SCHEMBL41788 | 0.78 | PNP (0.50) | PNPDPP4GDAPDPK1MAP3K5 | |
| SCHEMBL2051365 | 0.77 | PNP (0.49) | PNPDPP4GDAPDPK1MAP3K5 | |
| SCHEMBL20579 | 0.77 | DPP4 (0.50) | PNPDPP4GDAPDPK1MAP3K5 | |
| SCHEMBL8886040 | 0.77 | PNP (0.49) | PNPDPP4GDAPDPK1MAP3K5 | |
| SCHEMBL1843777 | 0.77 | PNP (0.49) | PNPDPP4GDAPDPK1MAP3K5 | |
| SCHEMBL2983851 | 0.77 | PNP (0.49) | PNPDPP4GDAPDPK1MAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1919858-A | Synthesis of 2'-deoxy-l-nucleosides | PHARMASSET LTD (US) | 2007-02-28 | — | — | CN | disclosed |
| CN-1919860-A | Synthesis of 2'-deoxy-l-nucleosides | PHARMASSET LTD (US) | 2007-02-28 | — | — | CN | disclosed |
| CN-1919859-A | Synthesis of 2'-deoxy-l-nucleosides | PHARMASSET LTD (US) | 2007-02-28 | — | — | CN | disclosed |
| CN-1423654-A | Synthesis of 2' -deoxy-L-nucleosides | PHARMASSET LTD (US) | 2003-06-11 | — | — | CN | disclosed |
| EP-0145739-B1 | NOVEL ANTIVIRAL AGENTS | SRI INTERNATIONAL (US) | 1989-02-08 | — | — | EP | disclosed |
| EP-0274025-A2 | Novel antiviral agents | SRI INTERNATIONAL (US) | 1988-07-13 | — | — | EP | disclosed |
| EP-0273169-A2 | Novel antiviral agents | SRI INTERNATIONAL (US) | 1988-07-06 | — | — | EP | disclosed |
| EP-0272446-A1 | Novel antiviral agents | SRI INTERNATIONAL (US) | 1988-06-29 | — | — | EP | disclosed |
| US-4323573-A | VIRICIDES | BURROUGHS WELLCOME CO. (US) | 1982-04-06 | — | — | US | disclosed |