Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.40 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28066958 | 0.85 | CYP1A2 (0.44) | PNPDPP4PDPK1GDAMAP3K5 | |
| SCHEMBL10597948 | 0.78 | PNP (0.46) | PNPDPP4PDPK1GDAMAP3K5 | |
| SCHEMBL20867 | 0.78 | ATAD2 (0.53) | PNPDPP4PDPK1GDACYP2C19 | |
| Water SCHEMBL27738785 | 0.76 | ADORA2A (0.54) | PNPDPP4PDPK1GDACYP2C19 | |
| Hydrochloric Acid SCHEMBL27339406 | 0.76 | ATAD2 (0.51) | PNPDPP4PDPK1GDACYP2C19 | |
| SCHEMBL2385669 | 0.76 | PNP (0.34) | PNPCYP2C19CYP1A2ATAD2ADORA2A | |
| SCHEMBL218669 | 0.76 | MGMT (0.45) | PNPDPP4PDPK1GDAMAP3K5 | |
| SCHEMBL41788 | 0.76 | PNP (0.50) | PNPDPP4PDPK1GDAMAP3K5 | |
| Sulfuric Acid SCHEMBL9697728 | 0.75 | CYP2C19 (0.43) | PNPDPP4PDPK1GDAMAP3K5 | |
| Bromide SCHEMBL8165615 | 0.75 | MGMT (0.44) | PNPDPP4PDPK1GDAMAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2552947-A2 | VISTA REGULATORY T CELL MEDIATOR PROTEIN, VISTA BINDING AGENTS AND USE THEREOF | Trustees of Dartmouth College (US) | 2013-02-06 | — | — | EP | disclosed |
| WO-2011120013-A2 | VISTA REGULATORY T CELL MEDIATOR PROTEIN, VISTA BINDING AGENTS AND USE THEREOF | TRUSTEES OF DARTMOUTH COLLEGE (US) | 2011-09-29 | — | — | WO | disclosed |
| WO-2005046661-A2 | USE OF NITRIC OXIDE DONORS FOR THE TREATMENT OF DRUG ADDICTION | UNIVERSITY OF SHEFFIELD (GB) | 2005-05-26 | — | — | WO | disclosed |
| EP-1450861-A2 | TARGETING NUCLEIC ACIDS TO A CELLULAR NUCLEUS | Mirus Corporation (US) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003012039-A2 | TARGETING NUCLEIC ACIDS TO A CELLULAR NUCLEUS | MIRUS CORPORATION (US) | 2003-02-13 | — | — | WO | disclosed |