SCHEMBL10598735

SCHEMBL10598735

NCCCC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)CCCCN)C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 1/20 0.41
▸ GNPAT O15228 1/20 0.40
▸ NMT1 P30419 5/20 0.39
▸ NMT2 O60551 4/20 0.39
▸ TERT O14746 1/20 0.39
▸ CD40 P25942 1/20 0.38
▸ ITGB3 P05106 1/20 0.38
▸ ITGA2B P08514 1/20 0.38
▸ TLR2 O60603 1/20 0.37
▸ SLC15A2 Q16348 1/20 0.37
▸ GSR P00390 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30616032 0.92 TERT (0.44) FOLH1GNPATTERTGSR
SCHEMBL5052423 0.92 NMT1 (0.46) FOLH1NMT1NMT2TERTTLR2
SCHEMBL5052434 0.92 NMT1 (0.46) FOLH1NMT1NMT2TERTTLR2
SCHEMBL10900479 0.91 FOLH1 (0.48) FOLH1GNPATGSR
SCHEMBL10900492 0.91 FOLH1 (0.48) FOLH1GNPATGSR
SCHEMBL31480035 0.90 FOLH1 (0.50) FOLH1GNPATNMT1NMT2
SCHEMBL29474449 0.89 FOLH1 (0.47) FOLH1GNPATTERTSLC15A2GSR
SCHEMBL31702941 0.88 FOLH1 (0.47) FOLH1GNPATTERTCD40GSR
SCHEMBL30099523 0.88 FOLH1 (0.50) FOLH1GNPATNMT1NMT2TERT
SCHEMBL29655368 0.88 FOLH1 (0.53) FOLH1GNPATNMT1NMT2SLC15A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0217919-A4 TYPE-SPECIFIC PAPILLOMAVIRUS DNA SEQUENCES AND PEPTIDES. UNIV GEORGETOWN (US) 1989-06-27 — — EP disclosed
EP-0217919-A1 TYPE-SPECIFIC PAPILLOMAVIRUS DNA SEQUENCES AND PEPTIDES. UNIV GEORGETOWN (US) 1987-04-15 — — EP disclosed
WO-1986005816-A1 TYPE-SPECIFIC PAPILLOMAVIRUS DNA SEQUENCES AND PEPTIDES GEORGETOWN UNIVERSITY (US) 1986-10-09 — — WO disclosed
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