Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | THRB | P10828 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | ODC1 | P11926 | 1/20 | 0.35 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.33 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | ARG1 | P05089 | 8/20 | 0.32 |
| ▸ | ARG2 | P78540 | 5/20 | 0.32 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27459648 | 0.86 | ALDH1A1 (0.65) | CYP1A2ALDH1A1THRBKMT2AMEN1 | |
| SCHEMBL9586044 | 0.84 | CYP1A2 (0.74) | CYP1A2ALDH1A1THRBKMT2AMEN1 | |
| SCHEMBL10512288 | 0.79 | ALDH1A1 (0.40) | CYP1A2ALDH1A1THRBKMT2AMEN1 | |
| SCHEMBL7021656 | 0.77 | CYP1A2 (0.65) | CYP1A2ALDH1A1THRBKMT2AMEN1 | |
| SCHEMBL10453104 | 0.77 | THRB (0.65) | CYP1A2ALDH1A1THRBKMT2AMEN1 | |
| SCHEMBL7021651 | 0.77 | CYP1A2 (0.65) | CYP1A2ALDH1A1THRBKMT2AMEN1 | |
| SCHEMBL7233790 | 0.77 | CYP1A2 (0.65) | CYP1A2ALDH1A1THRBKMT2AMEN1 | |
| SCHEMBL10453105 | 0.77 | THRB (0.65) | CYP1A2ALDH1A1THRBKMT2AMEN1 | |
| SCHEMBL10778584 | 0.76 | CYP1A2 (0.63) | CYP1A2ALDH1A1THRBKMT2AMEN1 | |
| SCHEMBL179812 | 0.76 | ALDH1A1 (1.00) | CYP1A2ALDH1A1THRBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0169812-B1 | PHOSPHATIDYL COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1989-08-23 | — | — | EP | claimed |