SCHEMBL10599343

SCHEMBL10599343

CC(=O)Nc1cccc(OCc2cccc(Br)c2)c1

nearest known ligand 0.70

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAOB P27338 9/20 0.70
MEN1 O00255 1/20 0.61
KMT2A Q03164 1/20 0.61
LMNA P02545 1/20 0.61
MAOA P21397 3/20 0.60
MRGPRX4 Q96LA9 1/20 0.56
NPC1 O15118 3/20 0.56
RAB9A P51151 3/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
ALDH1A1 P00352 1/20 0.56
MAPT P10636 1/20 0.56
F10 P00742 1/20 0.55
SIRT2 Q8IXJ6 1/20 0.55
SIRT3 Q9NTG7 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL595158 0.88 MAOB (0.64) MAOBMAOAMRGPRX4NPC1RAB9A
SCHEMBL10599853 0.86 MEN1 (0.79) MAOBMEN1KMT2ALMNANPC1
SCHEMBL10600206 0.84 MAOB (0.70) MAOBMEN1KMT2ALMNAMAOA
SCHEMBL595941 0.84 MAOB (0.59) MAOBMAOAMRGPRX4NPC1RAB9A
SCHEMBL13192625 0.84 MEN1 (0.64) MAOBMEN1KMT2ALMNANPC1
SCHEMBL10599166 0.81 LMNA (0.67) MAOBMEN1KMT2ALMNAMAOA
SCHEMBL11546092 0.78 SMN1; SMN2 (0.68) MEN1KMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL15472400 0.78 MEN1 (0.55) MAOBMEN1KMT2ALMNANPC1
SCHEMBL4404036 0.78 MAOB (1.00) MAOBMAOAMRGPRX4NPC1RAB9A
SCHEMBL264735 0.78 GAA (0.66) NPC1RAB9ASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0136678-B1 HEAT SENSITIVE RECORD MATERIAL HODOGAYA CHEMICAL CO., LTD. (JP) 1989-09-13 EP claimed
US-4539577-A Heat sensitive record material HODOGAYA CHEMICAL CO., LTD. (JP) 1985-09-03 US claimed
EP-0136678-A2 Heat sensitive record material HODOGAYA CHEMICAL CO., LTD. (JP) 1985-04-10 EP claimed
EP-0136678-B1 HEAT SENSITIVE RECORD MATERIAL HODOGAYA CHEMICAL CO., LTD. (JP) 1989-09-13 EP disclosed
US-4539577-A Heat sensitive record material HODOGAYA CHEMICAL CO., LTD. (JP) 1985-09-03 US disclosed
EP-0136678-A2 Heat sensitive record material HODOGAYA CHEMICAL CO., LTD. (JP) 1985-04-10 EP disclosed