Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 2/20 | 0.68 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.68 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.68 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.66 |
| ▸ | ABL1 | P00519 | 1/20 | 0.60 |
| ▸ | EGFR | P00533 | 1/20 | 0.60 |
| ▸ | ABL2 | P42684 | 1/20 | 0.60 |
| ▸ | MARS1 | P56192 | 1/20 | 0.60 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.59 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.59 |
| ▸ | SRC | P12931 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.59 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.59 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.59 |
| ▸ | LDHA | P00338 | 1/20 | 0.59 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.59 |
| ▸ | FBP1 | P09467 | 1/20 | 0.59 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL337873 | 0.86 | ABCB1 (0.75) | GSK3ARPS6KA3MAPK14ABCB1ABL1 | |
| SCHEMBL13268719 | 0.84 | ADORA1 (0.58) | P2RY1P2RY2ADORA1SRCSMN1; SMN2 | |
| SCHEMBL441535 | 0.84 | ABCB1 (0.77) | GSK3ARPS6KA3MAPK14ABCB1P2RY1 | |
| SCHEMBL11644877 | 0.84 | ABCB1 (0.77) | GSK3ARPS6KA3MAPK14ABCB1P2RY1 | |
| SCHEMBL13269505 | 0.83 | AHCY (0.57) | P2RY1P2RY2ADORA1SRCSMN1; SMN2 | |
| SCHEMBL31001632 | 0.82 | P2RY1 (0.71) | GSK3ARPS6KA3MAPK14ABCB1MARS1 | |
| SCHEMBL219554 | 0.82 | P2RY1 (0.71) | GSK3ARPS6KA3MAPK14ABCB1MARS1 | |
| SCHEMBL5550634 | 0.82 | P2RY1 (0.71) | GSK3ARPS6KA3MAPK14ABCB1MARS1 | |
| SCHEMBL11584743 | 0.82 | P2RY1 (0.71) | GSK3ARPS6KA3MAPK14ABCB1MARS1 | |
| SCHEMBL6425805 | 0.82 | ABCB1 (0.74) | GSK3ARPS6KA3MAPK14ABCB1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0175325-B1 | NEW 8-SUBSTITUTED NUCLEOSIDE AND PURINE DERIVATIVES, THE PROCESS FOR THE PREPARATION THEREOF AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Pierrel S.p.A. (IT) | 1989-03-15 | — | — | EP | disclosed |
| EP-0175325-A2 | New 8-substituted nucleoside and purine derivatives, the process for the preparation thereof and the pharmaceutical compositions containing them | Pierrel S.p.A. (IT) | 1986-03-26 | — | — | EP | disclosed |