SCHEMBL441535

SCHEMBL441535

Nc1ncnc2c1ncn2[C@@H]1O[C@H](COC(=O)c2ccccc2)[C@@H](O)[C@H]1O

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 1/20 0.77
GSK3A P49840 2/20 0.77
RPS6KA3 P51812 2/20 0.77
MAPK14 Q16539 2/20 0.77
ADORA1 P30542 4/20 0.67
DNPH1 O43598 1/20 0.65
PRKAB2 O43741 1/20 0.65
TRPM2 O94759 1/20 0.65
LDHA P00338 1/20 0.65
ADRB2 P07550 1/20 0.65
FBP1 P09467 1/20 0.65
SRC P12931 1/20 0.65
P2RY2 P41231 1/20 0.65
P2RY1 P47900 1/20 0.65
PRKAG1 P54619 1/20 0.65
PRKAA2 P54646 1/20 0.65
PDE4D Q08499 1/20 0.65
KCNH2 Q12809 1/20 0.65
PRKAA1 Q13131 1/20 0.65
PDE3A Q14432 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11644877 1.00 ABCB1 (0.77) ABCB1GSK3ARPS6KA3MAPK14ADORA1
SCHEMBL9501564 0.95 ABCB1 (0.71) ABCB1GSK3ARPS6KA3MAPK14ADORA1
SCHEMBL2205119 0.92 NT5E (0.69) ABCB1GSK3ARPS6KA3MAPK14ADORA1
SCHEMBL5983100 0.91 ENPP1 (0.71) ABCB1GSK3ARPS6KA3MAPK14ADORA1
SCHEMBL532929 0.91 ENPP1 (0.71) ABCB1GSK3ARPS6KA3MAPK14ADORA1
SCHEMBL5794949 0.91 ENPP1 (0.71) ABCB1GSK3ARPS6KA3MAPK14ADORA1
SCHEMBL532930 0.91 ENPP1 (0.71) ABCB1GSK3ARPS6KA3MAPK14ADORA1
SCHEMBL29169618 0.90 GSK3A (0.71) ABCB1GSK3ARPS6KA3MAPK14ADORA1
SCHEMBL14025772 0.90 ABCB1 (0.77) ABCB1GSK3ARPS6KA3MAPK14ADORA1
SCHEMBL4916919 0.90 ABCB1 (0.77) ABCB1GSK3ARPS6KA3MAPK14ADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 308 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117886868-A Preparation method of 5' -DMT nucleoside compound 天津奥瑞芙生物医药有限公司 2024-04-16 CN claimed
WO-2006038865-A1 NUCLEOTIDE DERIVATIVES FOR THE TREATMENT OF TYPE 2 DIABETES AND OTHER DISORDERS BETAGENON AB (SE) 2006-04-13 WO claimed
EP-0876388-B1 TRICYCLIC ERYTHROMYCIN DERIVATIVES ABBOTT LAB (US) 2004-02-18 EP claimed
US-12576099-B2 Ribose-modified cap analog and use thereof BEIJING YOUCARE KECHUANG PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) 2026-03-17 US disclosed
US-20260071217-A1 ANTISENSE OLIGOMER COMPOUNDS SAREPTA THERAPEUTICS, INC. (US) 2026-03-12 US disclosed
EP-4650358-A2 RIBOSE-MODIFIED CAP ANALOG AND USE THEREOF Beijing Youcare Kechuang Pharmaceutical Technology Co., Ltd. (CN) 2025-11-19 EP disclosed
US-12474327-B2 Metabolic profiling for the diagnosis of a subset of idiopathic autism spectrum disorder patients, ADS Phenotype 1 STALICLA SA (CH) 2025-11-18 US disclosed
US-20250332189-A1 RIBOSE-MODIFIED CAP ANALOG AND USE THEREOF BEIJING YOUCARE KECHUANG PHARMACEUTICAL TECH CO LTD (CN) 2025-10-30 US disclosed
US-20250241940-A1 MODIFIED ANTISENSE OLIGOMERS FOR EXON INCLUSION IN SPINAL MUSCULAR ATROPHY JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT 2025-07-31 US disclosed
US-20250171779-A1 ANTISENSE OLIGOMERS AND METHODS OF USING THE SAME FOR TREATING DISEASES ASSOCIATED WITH THE ACID ALPHA-GLUCOSIDASE GENE SAREPTA THERAPEUTICS, INC. (US) 2025-05-29 US disclosed
US-20250171783-A1 ANTISENSE-INDUCED EXON2 INCLUSION IN ACID ALPHA-GLUCOSIDASE SAREPTA THERAPEUTICS, INC. 2025-05-29 US disclosed
WO-1993003052-A1 MULTIDOMAIN DNA LIGANDS FOR PROTEIN AND NUCLEIC ACID AFFINITY CHROMATOGRAPHY AND PROCESSING OF SOLID-PHASE DNA ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 1993-02-18 WO disclosed
EP-0420872-A4 THERAPEUTIC USES OF 2',5'-OLIGOADENYLATE DERIVATIVES 1992-10-21 EP disclosed
WO-1991010671-A1 COMPOSITIONS AND METHODS FOR DETECTING AND MODULATING RNA ACTIVITY AND GENE EXPRESSION ISIS PHARMACEUTICALS, INC. (US) 1991-07-25 WO disclosed
EP-0420872-A1 THERAPEUTIC USES OF 2',5'-OLIGOADENYLATE DERIVATIVES. UNIV TEMPLE (US) 1991-04-10 EP disclosed
CN-1040321-A 2 ', 5 '-therapeutic use of oligomerization adenylic acid derivant UNIV TEMPLE (US) 1990-03-14 CN disclosed
EP-0270651-A4 NOVEL DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE FOR THE PREPARATION OF OLIGONUCLEOTIDES. CALIFORNIA INST OF TECHN (US) 1989-03-29 EP disclosed
EP-0270651-A1 NOVEL DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE FOR THE PREPARATION OF OLIGONUCLEOTIDES. CALIFORNIA INST OF TECHN (US) 1988-06-15 EP disclosed
WO-1988000201-A1 NOVEL DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE FOR THE PREPARATION OF OLIGONUCLEOTIDES CALIFORNIA INSTITUTE OF TECHNOLOGY, INC. (US) 1988-01-14 WO disclosed
EP-0121112-B1 2'-DEOXY-3-PHOSPHONYLMETHYL NUCLEOSIDES AND METHOD FOR THEIR PREPARATION Gesellschaft für Biotechnologische Forschung mbH (GBF) (DE) 1987-05-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12576099-B2 Ribose-modified cap analog and use thereof RNMT, RNGTT, NSUN2 ABCB1 2031/4885GSK3A 1157/4885RPS6KA3 116/4885
US-20260071217-A1 ANTISENSE OLIGOMER COMPOUNDS DCLRE1B, OGG1, DCTD ABCB1 497/4885GSK3A 2439/4885RPS6KA3 4196/4885
US-20250332189-A1 RIBOSE-MODIFIED CAP ANALOG AND USE THEREOF RNMT, RNGTT, CPSF1 ABCB1 2685/4885GSK3A 3051/4885RPS6KA3 274/4885
US-20250171779-A1 ANTISENSE OLIGOMERS AND METHODS OF USING THE SAME FOR TREATING DISEASES ASSOCIATED WITH THE ACID ALPHA-GLUCOSIDASE GENE GAA, GBA3, GBA1 ABCB1 1644/4885GSK3A 2533/4885RPS6KA3 3371/4885
US-20250241940-A1 MODIFIED ANTISENSE OLIGOMERS FOR EXON INCLUSION IN SPINAL MUSCULAR ATROPHY SMN1; SMN2, UPF1, RBM17 ABCB1 4557/4885GSK3A 2592/4885RPS6KA3 2789/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.