SCHEMBL10599552

SCHEMBL10599552

CC(Cc1ccccc1)c1ccccc1Cc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 8/20 0.52
TAAR1 Q96RJ0 5/20 0.52
SLC18A2 Q05940 1/20 0.52
SLC6A2 P23975 2/20 0.45
MAOA P21397 1/20 0.45
SLC6A4 P31645 1/20 0.45
SLC6A3 Q01959 1/20 0.45
CYP2A6 P11509 1/20 0.45
ADORA2A P29274 1/20 0.45
ADORA1 P30542 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.44
LMNA P02545 1/20 0.44
POLB P06746 1/20 0.42
MAPK1 P28482 1/20 0.42
CYP2D6 P10635 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6546197 0.85 SIGMAR1 (0.48) SIGMAR1TAAR1SLC18A2SLC6A2MAOA
SCHEMBL5664115 0.85 TSHR (0.52) SIGMAR1TAAR1SLC18A2L3MBTL1POLB
SCHEMBL855072 0.82 CYP2D6 (0.48) SIGMAR1TAAR1SLC18A2SLC6A2MAOA
SCHEMBL1160889 0.82 CYP2D6 (0.48) SIGMAR1TAAR1SLC18A2SLC6A2MAOA
SCHEMBL6546687 0.82 L3MBTL1 (0.47) SIGMAR1TAAR1SLC18A2SLC6A2MAOA
SCHEMBL6546357 0.81 SIGMAR1 (0.50) SIGMAR1TAAR1SLC18A2SLC6A2MAOA
Hydrogen Peroxide SCHEMBL29140083 0.80 L3MBTL1 (0.50) SLC6A2L3MBTL1LMNA
SCHEMBL21471624 0.80 L3MBTL1 (0.46) SIGMAR1TAAR1SLC18A2MAOAL3MBTL1
SCHEMBL10633863 0.80 SIGMAR1 (0.50) SIGMAR1TAAR1SLC18A2SLC6A2MAOA
Ammonia Solution, Strong SCHEMBL5299921 0.78 SIGMAR1 (0.48) SIGMAR1TAAR1SLC18A2SLC6A2MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0176366-B1 IMPREGNATED CAPACITOR NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-01-25 EP disclosed
US-4631632-A METALLIZED POLYPROPYLENE FILM IMPREGNATED WITH DIELECTRIC HAVING THREE CONDENSED OR NONCONDENSED AROMATIC RINGS NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1986-12-23 US disclosed
EP-0176366-A2 Impregnated capacitor NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1986-04-02 EP disclosed