SCHEMBL10599596

SCHEMBL10599596

CCN(CC)c1ccc(C2(c3c(C)n(C)c4ccccc34)OC(=O)c3ccccc32)c(OCc2ccccc2)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.37
BACE1 P56817 1/20 0.35
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 1/20 0.35
NPSR1 Q6W5P4 4/20 0.34
MAPT P10636 4/20 0.34
LMNA P02545 3/20 0.34
POLB P06746 1/20 0.34
ALOX12 P18054 1/20 0.34
GPR55 Q9Y2T6 1/20 0.34
HTT P42858 3/20 0.34
USP2 O75604 1/20 0.34
KDM4E B2RXH2 1/20 0.33
HCRTR1 O43613 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10592397 0.92 BACE1 (0.34) CYP3A4BACE1MEN1KMT2ANPC1
SCHEMBL8652758 0.92 CYP3A4 (0.43) CYP3A4MEN1KMT2ANPC1NPSR1
SCHEMBL10595050 0.91 CYP3A4 (0.36) CYP3A4BACE1MEN1KMT2ANPSR1
SCHEMBL10601107 0.86 CYP3A4 (0.35) CYP3A4BACE1MEN1KMT2ANPSR1
SCHEMBL29460366 0.85 MAPT (0.44) CYP3A4MEN1KMT2ANPC1NPSR1
SCHEMBL1370527 0.85 MAPT (0.44) CYP3A4MEN1KMT2ANPC1NPSR1
SCHEMBL10599863 0.85 CYP3A4 (0.38) CYP3A4MEN1KMT2AMAPTLMNA
SCHEMBL10599358 0.85 ALDH1A1 (0.36) CYP3A4MEN1KMT2ANPSR1MAPT
SCHEMBL10600279 0.85 BACE1 (0.36) CYP3A4BACE1MEN1KMT2ANPC1
SCHEMBL10336818 0.85 CYP3A4 (0.40) CYP3A4MEN1KMT2ANPSR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4800193-A ANILINE, INDOLE AND PHTHALEIN DYES; COLORFASTNESS; AROMATIC SOLVENT-SOLUBLE FUJI PHOTO FILM CO., LTD. (JP) 1989-01-24 US disclosed