Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.60 |
| ▸ | CD40 | P25942 | 1/20 | 0.55 |
| ▸ | CD40LG | P29965 | 1/20 | 0.55 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | MPL | P40238 | 1/20 | 0.44 |
| ▸ | CTRC | Q99895 | 1/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10600651 | 0.91 | PHLPP2 (0.51) | PHLPP2CD40CD40LGENPP2MEN1 | |
| SCHEMBL7591259 | 0.90 | PHLPP2 (0.61) | PHLPP2CD40CD40LGENPP2MEN1 | |
| SCHEMBL7766620 | 0.90 | PHLPP2 (0.61) | PHLPP2CD40CD40LGENPP2MEN1 | |
| SCHEMBL8035550 | 0.90 | PHLPP2 (0.57) | PHLPP2CD40CD40LGENPP2MEN1 | |
| SCHEMBL14466096 | 0.89 | CD40 (0.72) | PHLPP2CD40CD40LGENPP2MEN1 | |
| SCHEMBL8059751 | 0.89 | PHLPP2 (0.62) | PHLPP2CD40CD40LGENPP2MEN1 | |
| SCHEMBL7770984 | 0.89 | PHLPP2 (0.62) | PHLPP2CD40CD40LGENPP2MEN1 | |
| SCHEMBL8958917 | 0.88 | PHLPP2 (0.56) | PHLPP2CD40CD40LGENPP2MEN1 | |
| SCHEMBL8904069 | 0.88 | PHLPP2 (0.56) | PHLPP2CD40CD40LGENPP2MEN1 | |
| SCHEMBL14493323 | 0.87 | PHLPP2 (0.58) | PHLPP2CD40CD40LGENPP2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0131542-B1 | REACTIVE DYES, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1989-04-19 | — | — | EP | disclosed |
| EP-0131542-A1 | Reactive dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1985-01-16 | — | — | EP | disclosed |