Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.57 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.48 |
| ▸ | CD40 | P25942 | 1/20 | 0.47 |
| ▸ | CD40LG | P29965 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.43 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7770978 | 0.93 | PHLPP2 (0.54) | PHLPP2ENPP2CD40CD40LGMEN1 | |
| SCHEMBL10351775 | 0.93 | MEN1 (0.56) | PHLPP2ENPP2CD40CD40LGMEN1 | |
| SCHEMBL8070763 | 0.93 | PHLPP2 (0.54) | PHLPP2ENPP2CD40CD40LGMEN1 | |
| SCHEMBL10588141 | 0.91 | ENPP2 (0.49) | PHLPP2ENPP2CD40CD40LGMEN1 | |
| SCHEMBL7766620 | 0.90 | PHLPP2 (0.61) | PHLPP2ENPP2CD40CD40LGMEN1 | |
| SCHEMBL7591259 | 0.90 | PHLPP2 (0.61) | PHLPP2ENPP2CD40CD40LGMEN1 | |
| SCHEMBL10600174 | 0.90 | PHLPP2 (0.60) | PHLPP2ENPP2CD40CD40LGMEN1 | |
| SCHEMBL8904069 | 0.88 | PHLPP2 (0.56) | PHLPP2ENPP2CD40CD40LGMEN1 | |
| SCHEMBL8958917 | 0.88 | PHLPP2 (0.56) | PHLPP2ENPP2CD40CD40LGMEN1 | |
| SCHEMBL8779952 | 0.87 | CD40 (0.56) | PHLPP2ENPP2CD40CD40LGMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641839-B1 | Fiber-reactive dyes, their preparation and application | CIBA SC HOLDING AG (CH) | 2000-05-24 | — | — | EP | claimed |
| EP-0131542-B1 | REACTIVE DYES, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1989-04-19 | — | — | EP | disclosed |
| US-4818247-A | COLORFASTNESS | CIBA-GEIGY CORPORATION (US) | 1989-04-04 | — | — | US | disclosed |
| EP-0131542-A1 | Reactive dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1985-01-16 | — | — | EP | disclosed |