SCHEMBL10600205

SCHEMBL10600205

Cc1c(Cl)cc2c(c1Cl)C(=O)c1ccccc1C2=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 1/20 0.50
CYP1A2 P05177 1/20 0.50
TTR P02766 3/20 0.49
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
MAPT P10636 4/20 0.47
TDP1 Q9NUW8 3/20 0.47
POLB P06746 1/20 0.47
ELANE P08246 2/20 0.44
BCL2 P10415 2/20 0.43
MCL1 Q07820 2/20 0.43
ADORA2A P29274 1/20 0.43
CDC25B P30305 1/20 0.43
L3MBTL1 Q9Y468 4/20 0.42
RAB9A P51151 4/20 0.42
ALDH1A1 P00352 3/20 0.42
PTK2B Q14289 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
MAPK1 P28482 3/20 0.42
SMN1; SMN2 Q16637 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11404943 0.87 CYP1A1 (0.51) CYP1A1CYP1A2TTRMEN1KMT2A
SCHEMBL27706729 0.86 CYP1A1 (0.50) CYP1A1CYP1A2TTRMEN1KMT2A
SCHEMBL10729204 0.83 TTR (0.53) CYP1A1CYP1A2TTRMEN1KMT2A
SCHEMBL9846523 0.83 CYP1A1 (0.59) CYP1A1CYP1A2TTRMEN1KMT2A
SCHEMBL11790159 0.79 PGAM1 (0.48) CYP1A1CYP1A2TTRMEN1KMT2A
SCHEMBL10903041 0.79 MEN1 (0.61) CYP1A1CYP1A2TTRMEN1KMT2A
SCHEMBL12110293 0.77 IDO1 (0.52) CYP1A1CYP1A2MEN1KMT2AMAPT
SCHEMBL11222115 0.76 TTR (0.58) CYP1A1CYP1A2TTRMEN1KMT2A
SCHEMBL8876460 0.76 CYP1A1 (0.60) CYP1A1CYP1A2TTRMEN1KMT2A
SCHEMBL9095280 0.76 ADORA2A (0.47) CYP1A1CYP1A2TTRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4145356-A CRYSTALLIZATION IN SOLVENT CONTAINING AN ANTHRAQUINONE COMPOUND BASF AKTIENGESELLSCHAFT (DE) 1979-03-20 US claimed
EP-0136981-B1 PROCESS FOR THE PREPARATION OF ANTHRAQUINONE IMIDE COMPOUNDS CIBA-GEIGY AG (CH) 1989-04-05 EP disclosed
US-4659831-A Process for the preparation of anthraquinone imides CIBA-GEIGY AG (CH) 1987-04-21 US disclosed
EP-0136981-A2 Process for the preparation of anthraquinone imide compounds CIBA-GEIGY AG (CH) 1985-04-10 EP disclosed
US-4145356-A CRYSTALLIZATION IN SOLVENT CONTAINING AN ANTHRAQUINONE COMPOUND BASF AKTIENGESELLSCHAFT (DE) 1979-03-20 US disclosed