Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.50 |
| ▸ | AGXT | P21549 | 2/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27622323 | 0.81 | IDO1 (0.48) | IDO1AGXTNR4A2RAB9AMAOB | |
| SCHEMBL12786033 | 0.81 | TSHR (0.48) | IDO1AGXTNR4A2RAB9AMAOB | |
| SCHEMBL85540 | 0.80 | TSHR (0.63) | IDO1AGXTNR4A2RAB9ANPC1 | |
| SCHEMBL28120336 | 0.78 | IDO1 (0.45) | IDO1AGXTNR4A2RAB9AMAOB | |
| SCHEMBL31324508 | 0.78 | IDO1 (0.50) | IDO1AGXTNR4A2RAB9AMAOB | |
| SCHEMBL1242447 | 0.76 | TSHR (0.48) | IDO1AGXTNR4A2RAB9AMAOB | |
| SCHEMBL357428 | 0.76 | IDO1 (0.64) | IDO1AGXTNR4A2MAOBMAOA | |
| SCHEMBL6932050 | 0.75 | AKR1C3 (0.70) | IDO1RAB9AMAOBNPC1ALDH1A1 | |
| SCHEMBL28449328 | 0.75 | KMT2A (0.49) | IDO1AGXTNR4A2RAB9ANPC1 | |
| Dimethylamine SCHEMBL10912031 | 0.75 | RAB9A (0.49) | IDO1AGXTNR4A2RAB9AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150883-B1 | PROCESS FOR PREPARING N-(DIBENZYLOXYPHOSPHORYL)-CYANAMIDE AND PROCESSES USING SAID COMPOUNDS AS INTERMEDIATE FOR THE SYNTHESIS OF PHOSPHAGEN SUBSTANCES | F.I.S. FABBRICA ITALIANA SINTETICI S.p.A. (IT) | 1989-04-19 | — | — | EP | disclosed |