Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.33 |
| ▸ | MC3R | P41968 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17682185 | 0.77 | LMNA (0.50) | LMNAALDH1A1HTTPOLBADORA2B | |
| SCHEMBL19601295 | 0.76 | LMNA (0.49) | LMNAALDH1A1HTTPOLBADORA2B | |
| SCHEMBL11190463 | 0.75 | LMNA (0.46) | LMNAALDH1A1HTTPOLBADORA2B | |
| SCHEMBL23974577 | 0.74 | LMNA (0.54) | LMNAALDH1A1HTTPOLBADORA2B | |
| SCHEMBL3272841 | 0.72 | LMNA (0.54) | LMNAALDH1A1HTTPOLBADORA2B | |
| Isocaffiene SCHEMBL515995 | 0.71 | LMNA (0.57) | LMNAALDH1A1HTTPOLBADORA2B | |
| SCHEMBL1962417 | 0.70 | LMNA (0.69) | LMNAALDH1A1HTTPOLBADORA2B | |
| SCHEMBL8136340 | 0.68 | LMNA (0.54) | LMNAALDH1A1HTTPOLBADORA2B | |
| SCHEMBL28048679 | 0.68 | LMNA (0.54) | LMNAALDH1A1HTTPOLBADORA2B | |
| SCHEMBL11187813 | 0.67 | LMNA (0.52) | LMNAALDH1A1HTTPOLBADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0077896-B1 | THEOPHYLLINE DERIVATIVES, ANTIBODIES AND THEIR PREPARATION FROM THEOPHYLLINE IMMUNOGENS, AS WELL AS AN IMMUNO ASSAY METHOD AND REAGENT MEANS FOR DETERMINING THEOPHYLLINE | MILES INC. (US) | 1989-01-25 | — | — | EP | disclosed |
| US-4608336-A | DETERMINATION OF THEOPHYLLINE IN BIOLOGICAL FLUIDS | MILES LABORATORIES, INC. (US) | 1986-08-26 | — | — | US | disclosed |
| US-4533493-A | IMMUNOASSAYS FOR MEASUREMENT OF THEOPHYLLINE IN BIOLOGIACAL FLUIDS | MILES LABORATORIES, INC. (US) | 1985-08-06 | — | — | US | disclosed |
| US-4460772-A | IMMUNOASSAY | MILES LABORATORIES, INC. (US) | 1984-07-17 | — | — | US | disclosed |
| EP-0077896-A1 | Theophylline derivatives, antibodies and their preparation from theophylline immunogens, as well as an immuno assay method and reagent means for determining theophylline | MILES INC. (US) | 1983-05-04 | — | — | EP | disclosed |