Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.62 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | DHFR | P00374 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | ALB | P02768 | 1/20 | 0.62 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10768338 | 0.82 | KDM4E (0.48) | TTRACMSDKDM4EMEN1USP2 | |
| SCHEMBL14117521 | 0.81 | KDM4E (0.52) | TTRACMSDKDM4EMEN1USP2 | |
| SCHEMBL6205516 | 0.78 | TTR (0.53) | TTRACMSDKDM4EMEN1USP2 | |
| Diflunisal SCHEMBL4337 | 0.77 | ACMSD (1.00) | TTRACMSDKDM4EMEN1USP2 | |
| Diflunisal SCHEMBL29367380 | 0.77 | ACMSD (1.00) | TTRACMSDKDM4EMEN1USP2 | |
| Diflunisal SCHEMBL30509654 | 0.77 | ACMSD (1.00) | TTRACMSDKDM4EMEN1USP2 | |
| Diflunisal SCHEMBL3848363 | 0.77 | ACMSD (1.00) | TTRACMSDKDM4EMEN1USP2 | |
| Diflunisal SCHEMBL20876816 | 0.76 | ACMSD (0.97) | TTRACMSDKDM4EMEN1USP2 | |
| Diflunisal SCHEMBL28916416 | 0.76 | ACMSD (0.97) | TTRACMSDKDM4EMEN1USP2 | |
| Diflunisal SCHEMBL11425421 | 0.76 | ACMSD (0.97) | TTRACMSDKDM4EMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1684681-B1 | A MIXTURE FOR TRANSDERMAL DELIVERY OF LOW AND HIGH MOLECULAR WEIGHT COMPOUNDS | ORYXE (US) | 2018-10-24 | — | — | EP | claimed |
| EP-1765310-B1 | A MIXTURE FOR TRANSDERMAL DELIVERY OF LOW AND HIGH MOLECULAR WEIGHT COMPOUNDS | ORYXE (US) | 2015-10-28 | — | — | EP | claimed |
| EP-0144519-B1 | 2',4'-DIFLUORO-4-HYDROXY-(1,1'-DIPHENYL)-3-CARBOXYLIC DERIVATIVES OF N-ACETYLCYSTEINE AND OF S-CARBOXYMETHYLCYSTEINE HAVING ANTI-INFLAMMATORY AND MUCOLYTIC ACTIVITY, PROCESS FOR THEIR PREPARATION AND RELATED PHARMACEUTICAL COMPOSITIONS | LABORATORI GUIDOTTI S.P.A. (IT) | 1987-06-10 | — | — | EP | claimed |
| EP-0130514-A2 | Depot antiphlogistics | Troponwerke GmbH & Co. KG (DE) | 1985-01-09 | — | — | EP | claimed |
| EP-0132690-B1 | THERMOPLASTICS CONTAINING ANTIPHLOGISTICS | Troponwerke GmbH & Co. KG (DE) | 1989-02-01 | — | — | EP | disclosed |
| EP-0201828-A2 | Components for therapeutical drug delivery devices | BAYER AG (DE) | 1986-11-20 | — | — | EP | disclosed |
| EP-0132690-A1 | Thermoplastics containing antiphlogistics | Troponwerke GmbH & Co. KG (DE) | 1985-02-13 | — | — | EP | disclosed |
| EP-0024282-A1 | Benzoyl derivatives, their preparation and their use as medicines | Dr. Karl Thomae GmbH (DE) | 1981-03-04 | — | — | EP | disclosed |