SCHEMBL10600581

SCHEMBL10600581

CC(C)(C)OC(=O)O[Si](C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.38
DGAT1 O75907 1/20 0.37
USP2 O75604 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HDAC6 Q9UBN7 2/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC2 Q92769 1/20 0.34
GAA P10253 1/20 0.32
TSHR P16473 1/20 0.31
HSD17B10 Q99714 1/20 0.31
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18512605 0.82 ELANE (0.34) ELANEDGAT1USP2SMN1; SMN2HDAC6
SCHEMBL29743237 0.80 HDAC6 (0.34) ELANEDGAT1USP2SMN1; SMN2HDAC6
SCHEMBL29743250 0.79 ELANE (0.32) ELANEDGAT1HDAC6HDAC1HDAC2
SCHEMBL29743238 0.79 HDAC6 (0.33) ELANEDGAT1HDAC6HDAC1HDAC2
SCHEMBL5712009 0.78 ALDH1A1 (0.30)
SCHEMBL29121 0.78 DGAT1 (0.46) ELANEDGAT1USP2SMN1; SMN2HDAC6
SCHEMBL29743245 0.77 ELANE (0.34) ELANEDGAT1HDAC6HDAC1HDAC2
Ammonia Solution, Strong SCHEMBL9998492 0.76 DGAT1 (0.43) ELANEDGAT1USP2SMN1; SMN2HDAC6
Fluoride SCHEMBL2692246 0.76 DGAT1 (0.43) ELANEDGAT1USP2SMN1; SMN2HDAC6
Methyl Alcohol SCHEMBL28820308 0.76 DGAT1 (0.43) ELANEDGAT1USP2SMN1; SMN2HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220209301-A1 CARBONATE SOLVENTS FOR NON-AQUEOUS ELECTROLYTES FOR METAL AND METAL-ION BATTERIES SCE FRANCE (FR) 2022-06-30 US disclosed
EP-0198205-B1 PROCESS FOR THE PREPARATION OF ORGANOSILYL CARBONATES Wacker-Chemie GmbH (DE) 1989-05-31 EP disclosed