SCHEMBL10601015

SCHEMBL10601015

Brc1cccc2nc3ccccc3nc12

nearest known ligand 0.61

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 12/20 0.61
MAPT P10636 2/20 0.56
ALDH1A1 P00352 2/20 0.56
GAA P10253 1/20 0.56
RAB9A P51151 1/20 0.56
KMT2A Q03164 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56
ACHE P22303 1/20 0.44
BACE1 P56817 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24276712 0.93 NQO2 (0.50) NQO2MAPTALDH1A1GAARAB9A
SCHEMBL28320380 0.90 NQO2 (0.48) NQO2MAPTALDH1A1GAARAB9A
SCHEMBL30504380 0.88 NQO2 (0.47) NQO2MAPTALDH1A1GAARAB9A
SCHEMBL28967302 0.88 NQO2 (0.47) NQO2MAPTALDH1A1GAARAB9A
SCHEMBL28667228 0.84 NQO2 (0.59) NQO2MAPTALDH1A1GAARAB9A
SCHEMBL24276707 0.84 NQO2 (0.59) NQO2MAPTALDH1A1GAARAB9A
SCHEMBL31260124 0.84 NQO2 (0.59) NQO2MAPTALDH1A1GAARAB9A
SCHEMBL19988780 0.82 NQO2 (0.75) NQO2MAPTALDH1A1GAARAB9A
SCHEMBL23612578 0.80 ACHE (0.75) NQO2MAPTALDH1A1GAARAB9A
SCHEMBL15228704 0.77 TDP1 (0.52) NQO2MAPTALDH1A1GAARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117736153-A Phenazine derivative, method for producing the same, electron mediator, and sensor 南京晶捷生物科技有限公司 2024-03-22 CN claimed
EP-0214330-B1 METHOD FOR IMMOBILIZING SUBSTANCES IN SYNTHETIC SOLID PHASES, AND SYNTHETIC SOLID PHASES FOR USE IN IMMUNOSORBENT ASSAYS PROGEN Biotechnik GmbH (DE) 1989-04-26 EP claimed
EP-0214330-A1 Method for immobilizing substances in synthetic solid phases, and synthetic solid phases for use in immunosorbent assays PROGEN Biotechnik GmbH (DE) 1987-03-18 EP claimed
CN-121293152-B Organic light-emitting compound, organic electroluminescent composition, light-emitting device and display device 季华实验室 2026-05-19 CN disclosed
US-12060334-B2 3-substituted phenazine derivatives as antimicrobial agents UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2024-08-13 US disclosed
CN-117736153-A Phenazine derivative, method for producing the same, electron mediator, and sensor 南京晶捷生物科技有限公司 2024-03-22 CN disclosed
US-20220289689-A1 3-SUBSTITUTED PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED 2022-09-15 US disclosed
CN-111303056-B Phenazine group-substituted polycyclic aromatic hydrocarbon derivative and application thereof 北京鼎材科技有限公司 2022-02-11 CN disclosed
CN-111253393-B Long-life triplet exciton confinement material and application thereof in OLED (organic light emitting diode) device 北京大学 2022-01-25 CN disclosed
US-11053205-B2 Phenazine derivatives as antimicrobial agents UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2021-07-06 US disclosed
CN-107915687-B High-efficiency preparation method of polysubstituted phenazine derivative and oxide thereof 清华大学 2021-02-26 CN disclosed
WO-2018152436-A1 PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS UNIVERSITY OF RESEARCH FOUNDATION, INCORPORATED (US) 2018-08-23 WO disclosed
US-9856225-B2 Substituted phenazines as antimicrobial agents UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2018-01-02 US disclosed
WO-2017011730-A2 PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2017-01-19 WO disclosed
US-20160355487-A1 PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2016-12-08 US disclosed
EP-3086791-A2 PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS University of Florida Research Foundation, Inc. (US) 2016-11-02 EP disclosed
WO-2016154051-A1 COMBINATION THERAPY FOR TREATING INFECTIONS DISEASES UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2016-09-29 WO disclosed
WO-2015100331-A2 PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-07-02 WO disclosed
EP-0214330-B1 METHOD FOR IMMOBILIZING SUBSTANCES IN SYNTHETIC SOLID PHASES, AND SYNTHETIC SOLID PHASES FOR USE IN IMMUNOSORBENT ASSAYS PROGEN Biotechnik GmbH (DE) 1989-04-26 EP disclosed
EP-0214330-A1 Method for immobilizing substances in synthetic solid phases, and synthetic solid phases for use in immunosorbent assays PROGEN Biotechnik GmbH (DE) 1987-03-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220289689-A1 3-SUBSTITUTED PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS ROS1, NOX4, NOX5 NQO2 139/4885MAPT 3143/4885ALDH1A1 348/4885
US-11053205-B2 Phenazine derivatives as antimicrobial agents ROS1, NOX4, PRDX3 NQO2 172/4885MAPT 2601/4885ALDH1A1 701/4885
US-20160355487-A1 PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS ROS1, NOX4, NOX5 NQO2 349/4885MAPT 3475/4885ALDH1A1 1136/4885
US-12060334-B2 3-substituted phenazine derivatives as antimicrobial agents ROS1, NOX4, NOX5 NQO2 139/4885MAPT 3143/4885ALDH1A1 348/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.