SCHEMBL10601780

SCHEMBL10601780

CCCCCCCCCCCCNC(=O)C(C#N)=CC=C1CCCN1CC

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 3/20 0.44
▸ HPGD P15428 5/20 0.43
▸ ALDH1A1 P00352 2/20 0.43
▸ LMNA P02545 3/20 0.41
▸ MEN1 O00255 1/20 0.41
▸ TP53 P04637 1/20 0.41
▸ HSP90AA1 P07900 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ ATM Q13315 1/20 0.41
▸ DNM2 P50570 3/20 0.40
▸ KDM4E B2RXH2 1/20 0.38
▸ DNM1 Q05193 9/20 0.38
▸ EGFR P00533 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26338674 1.00 SMN1; SMN2 (0.44) SMN1; SMN2HPGDALDH1A1LMNAMEN1
SCHEMBL14254898 1.00 SMN1; SMN2 (0.44) SMN1; SMN2HPGDALDH1A1LMNAMEN1
SCHEMBL10603923 0.83 SMN1; SMN2 (0.41) SMN1; SMN2HPGDALDH1A1LMNAMEN1
SCHEMBL19240050 0.72 NAAA (0.39) KDM4E
SCHEMBL25477357 0.71 MEN1 (0.38) SMN1; SMN2HPGDALDH1A1LMNAMEN1
SCHEMBL17897735 0.71 MEN1 (0.38) SMN1; SMN2HPGDALDH1A1LMNAMEN1
SCHEMBL12758194 0.69 HPGD (0.45) SMN1; SMN2HPGDALDH1A1LMNAMEN1
SCHEMBL8763697 0.68 SMN1; SMN2 (0.54) SMN1; SMN2HPGDALDH1A1LMNAMEN1
SCHEMBL9287155 0.68 SMN1; SMN2 (0.54) SMN1; SMN2HPGDALDH1A1LMNAMEN1
SCHEMBL8763694 0.68 SMN1; SMN2 (0.54) SMN1; SMN2HPGDALDH1A1LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0116428-B1 SILVER HALIDE PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL KONICA CORPORATION (JP) 1989-03-22 — — EP disclosed
EP-0088563-B1 LIGHT-SENSITIVE SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL KONICA CORPORATION (JP) 1987-09-23 — — EP disclosed
EP-0102839-B1 SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL KONICA CORPORATION (JP) 1987-02-04 — — EP disclosed
EP-0087931-B1 LIGHT-SENSITIVE SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL KONICA CORPORATION (JP) 1986-06-25 — — EP disclosed
US-4554247-A FINE OIL GLOBULES AND HARDENER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1985-11-19 — — US disclosed
US-4551422-A COLOR FILMS; PHENOLIC COUPLERS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1985-11-05 — — US disclosed
US-4518683-A A CARBOXAMIDO-UREIDO-SUBSTITUTED PHENOLIC CYAN COUPLER AND A PHTHALATE; PRESERVABILITY UNDER HIGH HEAT AND HUMIDITY AGING CONDITIONS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1985-05-21 — — US disclosed
US-4490460-A FORMALDEHYDE-RESISTANT KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1984-12-25 — — US disclosed
US-4480028-A CONTAINING CHELATING AGENT, SOIL SUSPENDER, HYDROTROPE AND DETERGENT KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1984-10-30 — — US disclosed
EP-0116428-A2 Silver halide photographic light-sensitive material KONICA CORPORATION (JP) 1984-08-22 — — EP disclosed
EP-0102839-A1 Silver halide color photographic light-sensitive material KONICA CORPORATION (JP) 1984-03-14 — — EP disclosed
EP-0087984-A2 A silver halide color photographic material KONICA CORPORATION (JP) 1983-09-07 — — EP disclosed
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