Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3262986 | 0.77 | CYP2D6 (0.34) | LMNARIPK1HTR2ATAAR1CYP2D6 | |
| SCHEMBL27081817 | 0.72 | RIPK1 (0.36) | TRPA1LMNARIPK1HTR2ATAAR1 | |
| SCHEMBL28077691 | 0.71 | CYP2D6 (0.39) | LMNARIPK1HTR2ATAAR1CYP2D6 | |
| SCHEMBL1716440 | 0.69 | CYP2D6 (0.43) | LMNAALDH1A1CYP2D6KMT2A | |
| SCHEMBL28825924 | 0.68 | CYP2D6 (0.37) | LMNARIPK1HTR2ATAAR1CYP2D6 | |
| SCHEMBL11476137 | 0.68 | CYP2D6 (0.41) | LMNARIPK1CYP2D6KMT2A | |
| SCHEMBL1225030 | 0.67 | CYP2D6 (0.39) | LMNAHTR2ATAAR1CYP2D6KMT2A | |
| SCHEMBL2433066 | 0.67 | EDNRB (0.40) | TRPA1LMNAALDH1A1MAPTCYP2D6 | |
| SCHEMBL24723643 | 0.66 | RIPK1 (0.35) | LMNARIPK1HTR2ATAAR1ALDH1A1 | |
| SCHEMBL10433996 | 0.66 | CYP2C19 (0.37) | RIPK1HTR2ATAAR1CYP2D6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219901-B1 | PERFUME COMPOSITIONS AND PERFUMED PRODUCTS WHICH CONTAIN AN ALKYL 2-MERCAPTOBENZOATE AS BASIC COMPONENT | NAARDEN INTERNATIONAL N.V. (NL) | 1989-04-19 | — | — | EP | disclosed |
| US-4749682-A | SOAPS, DETERGENTS, COSMETICS, HAIR PRODUCTS, CANDLES | NAARDEN INTERNATIONAL N.V. (NL) | 1988-06-07 | — | — | US | disclosed |
| EP-0219901-A1 | Perfume compositions and perfumed products which contain an alkyl 2-mercaptobenzoate as basic component | NAARDEN INTERNATIONAL N.V. (NL) | 1987-04-29 | — | — | EP | disclosed |