SCHEMBL1716440

SCHEMBL1716440

CC(C)(C(=O)O)C(C=O)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.43
LMNA P02545 4/20 0.42
MAPK1 P28482 1/20 0.42
KMT2A Q03164 1/20 0.41
CYP2C19 P33261 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
SRC P12931 1/20 0.39
ATM Q13315 1/20 0.39
CES2 O00748 2/20 0.38
CES1 P23141 2/20 0.38
AOC3 Q16853 1/20 0.38
OPRK1 P41145 1/20 0.36
ALDH1A1 P00352 1/20 0.36
CYP3A4 P08684 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11476137 0.80 CYP2D6 (0.41) CYP2D6LMNAMAPK1KMT2ACYP2C19
SCHEMBL28077691 0.79 CYP2D6 (0.39) CYP2D6LMNAMAPK1KMT2AL3MBTL1
SCHEMBL30416395 0.76 CYP3A4 (0.44) LMNAMAPK1KMT2ACYP2C19L3MBTL1
SCHEMBL28825924 0.76 CYP2D6 (0.37) CYP2D6LMNAMAPK1KMT2ACYP2C19
SCHEMBL11663964 0.75 L3MBTL1 (0.45) CYP2D6LMNAMAPK1KMT2ACYP2C19
SCHEMBL9683893 0.75 AOC3 (0.57) CYP2D6LMNAMAPK1KMT2AL3MBTL1
SCHEMBL60356 0.75 AOC3 (0.57) CYP2D6LMNAMAPK1KMT2AL3MBTL1
SCHEMBL2896278 0.75 NR3C1 (0.47) CYP2D6LMNAMAPK1KMT2AL3MBTL1
SCHEMBL173884 0.74 L3MBTL1 (0.43) CYP2D6LMNAMAPK1KMT2AL3MBTL1
SCHEMBL7836925 0.74 AOC3 (0.46) CYP2D6LMNACYP2C19L3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1299500-B1 METHOD AND APPARATUS FOR DELIVERING A VOLATILE COMPONENT VIA A CONTROLLED EXOTHERMIC REACTION PROCTER & GAMBLE (US) 2012-01-18 EP claimed
EP-1363678-B1 COMPOSITION FOR AROMA DELIVERY WITH IMPROVED STABILITY AND REDUCED FOAMING PROCTER & GAMBLE (US) 2005-05-18 EP claimed
EP-0908439-B1 Use of substituted 5-phenyl-pentanols as flavour and perfume HAARMANN & REIMER GMBH (DE) 2003-01-02 EP disclosed
EP-1034705-A2 Encapsulating medium and method for encapsulating perfumes and flavours HAARMANN & REIMER GMBH (DE) 2000-09-13 EP disclosed
EP-0908439-A1 Use of substituted 5-phenyl-pentanols as flavour and perfume HAARMANN & REIMER GMBH (DE) 1999-04-14 EP disclosed
EP-0137793-A1 2,6-EXO CONFIGURED TRICYCLO (5.2.1.0(2,6)) DECANE DERIVATIVES WITH FUNCTIONAL SIDE CHAIN IN C-8/C-9 AND UTILIZATION THEREOF AS PERFUMES. DRAGOCO GERBERDING CO GMBH (DE) 1985-04-24 EP disclosed
WO-1984003086-A1 2,6-EXO CONFIGURED TRICYCLO AD5.2.1.02,6 BDDECANE DERIVATIVES WITH FUNCTIONAL SIDE CHAIN IN C-8/C-9 AND UTILIZATION THEREOF AS PERFUMES DRAGOCO GERBERDING CO GMBH (DE) 1984-08-16 WO disclosed