Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 1/20 | 0.46 |
| ▸ | RARG | P13631 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | PTGIR | P43119 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10603408 | 1.00 | NR4A2 (0.50) | NR4A2TRPA1PPARGGPR132PTGER4 | |
| SCHEMBL10608251 | 0.94 | TRPA1 (0.40) | NR4A2TRPA1PPARGGPR132PTGER4 | |
| SCHEMBL10608248 | 0.94 | TRPA1 (0.40) | NR4A2TRPA1PPARGGPR132PTGER4 | |
| SCHEMBL10605176 | 0.90 | TRPA1 (0.38) | NR4A2TRPA1PPARGGPR132MEN1 | |
| SCHEMBL10605177 | 0.90 | TRPA1 (0.38) | NR4A2TRPA1PPARGGPR132MEN1 | |
| SCHEMBL10603560 | 0.89 | NR4A2 (0.39) | NR4A2TRPA1PPARGGPR132PTGER4 | |
| SCHEMBL10603544 | 0.88 | PTGIR (0.47) | NR4A2TRPA1PPARGGPR132PTGER4 | |
| SCHEMBL10603539 | 0.88 | PTGIR (0.47) | NR4A2TRPA1PPARGGPR132PTGER4 | |
| SCHEMBL10605122 | 0.88 | NR4A2 (0.39) | NR4A2TRPA1PPARGGPR132PTGER4 | |
| SCHEMBL10605252 | 0.88 | TRPA1 (0.39) | NR4A2TRPA1PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0131441-B1 | 5-ALKYLIDENE-2-HALO-4-SUBSTITUTED-2-CYCLOPENTENONE AND PROCESS FOR PRODUCTION THEREOF | TEIJIN LIMITED (JP) | 1989-10-18 | — | — | EP | disclosed |
| US-4689426-A | ANTITUMOR AGENTS, VIRCIDES, BACTERICIDES | TEIJIN LIMITED (JP) | 1987-08-25 | — | — | US | disclosed |