Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 6/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.36 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10603544 | 1.00 | PTGIR (0.47) | PTGIRTRPA1NR4A2PTGER4PTGER3 | |
| SCHEMBL10603408 | 0.88 | NR4A2 (0.50) | PTGIRTRPA1NR4A2PTGER4PTGER3 | |
| SCHEMBL10603403 | 0.88 | NR4A2 (0.50) | PTGIRTRPA1NR4A2PTGER4PTGER3 | |
| SCHEMBL10605053 | 0.84 | PTGER4 (0.35) | PTGIRTRPA1PTGER4PTGER3PTGER2 | |
| SCHEMBL10603623 | 0.84 | PTGER4 (0.35) | PTGIRTRPA1PTGER4PTGER3PTGER2 | |
| SCHEMBL10619857 | 0.83 | PTGIR (0.49) | PTGIRTRPA1NR4A2ABHD16APPARG | |
| SCHEMBL10619854 | 0.83 | PTGIR (0.49) | PTGIRTRPA1NR4A2ABHD16APPARG | |
| SCHEMBL10608251 | 0.82 | TRPA1 (0.40) | TRPA1NR4A2PTGER4PTGER3PTGER2 | |
| SCHEMBL10608248 | 0.82 | TRPA1 (0.40) | TRPA1NR4A2PTGER4PTGER3PTGER2 | |
| SCHEMBL10606550 | 0.82 | PPARG (0.50) | NR4A2PPARGCYP3A4HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0131441-B1 | 5-ALKYLIDENE-2-HALO-4-SUBSTITUTED-2-CYCLOPENTENONE AND PROCESS FOR PRODUCTION THEREOF | TEIJIN LIMITED (JP) | 1989-10-18 | — | — | EP | disclosed |
| US-4689426-A | ANTITUMOR AGENTS, VIRCIDES, BACTERICIDES | TEIJIN LIMITED (JP) | 1987-08-25 | — | — | US | disclosed |
| EP-0131441-A2 | 5-Alkylidene-2-halo-4-substituted-2-cyclopentenone and process for production thereof | TEIJIN LIMITED (JP) | 1985-01-16 | — | — | EP | disclosed |