Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.49 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.47 |
| ▸ | EYA3 | Q99504 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | TTR | P02766 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1520307 | 0.80 | KMT2A (0.50) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| SCHEMBL1648026 | 0.79 | CA12 (0.58) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| SCHEMBL7753264 | 0.78 | CA12 (0.57) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| SCHEMBL7839863 | 0.78 | KDM4E (0.47) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| SCHEMBL1398779 | 0.78 | CYP2C19 (0.63) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| SCHEMBL5579331 | 0.77 | KDM4E (0.57) | KDM4ECA12CA9HSD17B10ALDH1A1 | |
| SCHEMBL29901650 | 0.76 | CA12 (0.73) | KDM4ECYP2C19CA12CA9ALDH1A1 | |
| SCHEMBL1648027 | 0.76 | CA12 (0.73) | KDM4ECYP2C19CA12CA9ALDH1A1 | |
| SCHEMBL4670184 | 0.74 | EYA3 (0.66) | USP2PTGS1CYP2C19EYA3TTR | |
| SCHEMBL3537107 | 0.74 | CYP2C9 (0.50) | KDM4EUSP2CSNK2A2PTGS1CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0200187-B1 | PROCESS FOR THE PREPARATION OF 2-HYDROXY-DIBENZOFURAN-3-CARBOXYLIC ACID OR ITS ALKALI SALTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-06-07 | — | — | EP | claimed |
| EP-0200187-A2 | Process for the preparation of 2-hydroxy-dibenzofuran-3-carboxylic acid or its alkali salts | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-11-05 | — | — | EP | claimed |