Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 2/20 | 0.55 |
| ▸ | TUBB | P07437 | 2/20 | 0.55 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.55 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.55 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.55 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.55 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.55 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.55 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.55 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.55 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.55 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.55 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.55 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.55 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 8/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10604146 | 1.00 | TUBB4A (0.55) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7969707 | 0.87 | TUBB4A (0.71) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7969700 | 0.87 | TUBB4A (0.71) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7966880 | 0.87 | TUBB4A (0.63) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7966885 | 0.87 | TUBB4A (0.63) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL22510999 | 0.85 | ALDH1A1 (0.60) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7746900 | 0.80 | KMT2A (0.67) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7746901 | 0.80 | KMT2A (0.67) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL18422219 | 0.79 | HDAC3 (0.55) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL18422215 | 0.79 | HDAC3 (0.55) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4837305-A | Derivatives of β-adrenergic antagonists | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1989-06-06 | — | — | US | disclosed |
| EP-0117089-B1 | BETA-ADRENERGIC ANTAGONIST COMPOUNDS AND DERIVATIVES OF BETA-ADRENERGIC ANTAGONISTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1988-12-14 | — | — | EP | disclosed |
| US-4687873-A | Derivatives of β-adrenergic antagonists | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1987-08-18 | — | — | US | disclosed |
| EP-0117089-A1 | Beta-adrenergic antagonist compounds and derivatives of beta-adrenergic antagonists | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1984-08-29 | — | — | EP | disclosed |