Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25800279 | 0.82 | SLC9A1 (0.42) | ALDH1A1CYP2C9CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL25808818 | 0.76 | SLC9A1 (0.41) | ALDH1A1CYP2C9CYP4Z1USP2CCNE1 | |
| SCHEMBL10607208 | 0.72 | SLC9A1 (0.52) | ALDH1A1CYP2C9CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8631035 | 0.72 | MAPT (0.52) | ALDH1A1CYP2C9CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL19257190 | 0.70 | POLB (0.46) | ALDH1A1USP2CCNE1CDK2MAPK8 | |
| SCHEMBL10605617 | 0.69 | MAPT (0.48) | ALDH1A1CYP2C9CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL29152989 | 0.69 | USP2 (0.66) | ALDH1A1CYP3A4CYP2D6MAPTUSP2 | |
| SCHEMBL16372562 | 0.69 | USP2 (0.66) | ALDH1A1CYP3A4CYP2D6MAPTUSP2 | |
| SCHEMBL241247 | 0.69 | CCNE1 (0.49) | ALDH1A1CYP4Z1USP2CCNE1CDK2 | |
| SCHEMBL10606076 | 0.68 | SLC9A1 (0.51) | ALDH1A1CYP2C9CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0205398-B1 | ADDITIVE FOR FUNCTIONAL FLUIDS | CIBA-GEIGY AG (CH) | 1989-11-08 | — | — | EP | disclosed |
| US-4791206-A | METAL PASSIVATING, OXIDATION RESISTANCE | CIBA-GEIGY CORPORATION (US) | 1988-12-13 | — | — | US | disclosed |
| EP-0205398-A1 | Additive for functional fluids | CIBA-GEIGY AG (CH) | 1986-12-17 | — | — | EP | disclosed |