Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9640365 | 0.73 | — | — | |
| SCHEMBL11042255 | 0.65 | FFAR3 (0.35) | FFAR3 | |
| SCHEMBL10604385 | 0.65 | APLNR (0.31) | — | |
| Bicarbonate SCHEMBL10867748 | 0.65 | MAPK1 (0.33) | FFAR3 | |
| SCHEMBL5509512 | 0.63 | — | — | |
| Bicarbonate SCHEMBL9628771 | 0.61 | MAPK1 (0.33) | FFAR3 | |
| Bicarbonate SCHEMBL28280718 | 0.61 | — | — | |
| Bicarbonate SCHEMBL9303939 | 0.61 | FFAR3 (0.50) | FFAR3 | |
| Bicarbonate SCHEMBL10865056 | 0.60 | CA1 (0.36) | FFAR3 | |
| Bicarbonate SCHEMBL10865371 | 0.60 | MAPK1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0170842-B1 | N-BENZYLCYCLOPROPANECARBOXAMIDE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND FUNGICIDES FOR AGRICULTURE AND HORTICULTURE | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1989-09-13 | — | — | EP | disclosed |