Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.61 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.50 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3542328 | 0.95 | ALDH1A1 (0.57) | ALDH1A1KMT2AMEN1MTNR1AMTNR1B | |
| SCHEMBL8190937 | 0.94 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1MTNR1AMTNR1B | |
| SCHEMBL14027267 | 0.91 | ALDH1A1 (0.72) | ALDH1A1KMT2AMEN1MTNR1AMTNR1B | |
| SCHEMBL29944228 | 0.91 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1MTNR1AMTNR1B | |
| SCHEMBL14027269 | 0.91 | ALDH1A1 (0.72) | ALDH1A1KMT2AMEN1MTNR1AMTNR1B | |
| SCHEMBL18736058 | 0.90 | MTNR1A (0.72) | ALDH1A1KMT2AMEN1MTNR1AMTNR1B | |
| SCHEMBL8192655 | 0.90 | KMT2A (0.66) | ALDH1A1KMT2AMEN1MTNR1AMTNR1B | |
| SCHEMBL10601391 | 0.90 | ALDH1A1 (0.55) | ALDH1A1KMT2AMEN1MTNR1AMTNR1B | |
| SCHEMBL10604740 | 0.90 | CA1 (0.58) | ALDH1A1KMT2AMEN1MTNR1AMTNR1B | |
| SCHEMBL8190867 | 0.90 | ALDH1A1 (0.55) | ALDH1A1KMT2AMEN1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0167204-B1 | METHOD FOR IMPROVING THE ABSORPTION AND EFFECTIVENESS OF A CATECHOLAMINE COMPOUND | SIMES S.p.A. Società Italiana Medicinali e Sintetici (IT) | 1989-09-27 | — | — | EP | disclosed |
| US-4673671-A | CONVERSION TO MONO O-PHOSPHATE ESTER | SIMES SOCIETA ITALIANA MEDICINALI E SINTETICI S.P.A. (IT) | 1987-06-16 | — | — | US | disclosed |