Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | NOS1 | P29475 | 1/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 7/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6174346 | 0.90 | HRH3 (0.60) | HRH3CYP19A1KDM4EALDH1A1MAPK1 | |
| SCHEMBL6172429 | 0.83 | HRH3 (0.55) | HRH3CYP19A1KDM4EALDH1A1MAPK1 | |
| SCHEMBL6174918 | 0.80 | CYP19A1 (0.52) | CYP19A1KDM4EALDH1A1MAPK1TBXAS1 | |
| SCHEMBL6171877 | 0.79 | MAOB (0.56) | CYP19A1KDM4EALDH1A1MAPK1TBXAS1 | |
| SCHEMBL4823867 | 0.79 | TBXAS1 (0.48) | CYP19A1TBXAS1KMT2A | |
| SCHEMBL577896 | 0.77 | KDM4E (0.58) | CYP19A1KDM4EALDH1A1MAPK1NOS1 | |
| SCHEMBL330239 | 0.76 | KDM4E (0.57) | CYP19A1KDM4EALDH1A1MAPK1NOS1 | |
| SCHEMBL6753943 | 0.76 | HMOX1 (0.53) | CYP19A1TBXAS1 | |
| SCHEMBL4819893 | 0.76 | CYP17A1 (0.56) | CYP19A1TBXAS1 | |
| SCHEMBL6173341 | 0.75 | CYP19A1 (0.60) | CYP19A1ALDH1A1MAPK1NOS1PDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4610998-A | Imidazolylethoxyindanes and use as antithrombotic agents | FERRER INTERNACIONAL, S.A. (ES) | 1986-09-09 | — | — | US | claimed |
| EP-0184809-B1 | IMIDAZOLYLALKOXYINDANIC DERIVATIVES, A PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | FERRER INTERNACIONAL, S.A. (ES) | 1989-08-02 | — | — | EP | disclosed |
| US-4610998-A | Imidazolylethoxyindanes and use as antithrombotic agents | FERRER INTERNACIONAL, S.A. (ES) | 1986-09-09 | — | — | US | disclosed |
| EP-0184809-A1 | Imidazolylalkoxyindanic derivatives, a process for preparing them and pharmaceutical composition containing them | FERRER INTERNACIONAL, S.A. (ES) | 1986-06-18 | — | — | EP | disclosed |