Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10608854 | 0.79 | KMT2A (0.73) | KMT2ARAB9AMAPK1SMN1; SMN2POLB | |
| SCHEMBL18527815 | 0.78 | KMT2A (0.72) | KMT2ARAB9AMAPK1SMN1; SMN2POLB | |
| SCHEMBL18527818 | 0.78 | KMT2A (0.72) | KMT2ARAB9AMAPK1SMN1; SMN2POLB | |
| SCHEMBL10603852 | 0.76 | KMT2A (0.70) | KMT2ARAB9ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL10603968 | 0.76 | KMT2A (0.69) | KMT2ARAB9AMAPK1SMN1; SMN2POLB | |
| SCHEMBL11195417 | 0.75 | KMT2A (0.60) | KMT2ARAB9AMAPK1SMN1; SMN2POLB | |
| Hydrochloric Acid SCHEMBL10604021 | 0.74 | NPC1 (0.45) | KMT2ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL9166449 | 0.74 | KMT2A (0.70) | KMT2ARAB9AMAPK1SMN1; SMN2POLB | |
| SCHEMBL7163322 | 0.72 | MAPK1 (0.59) | MAPK1POLBALDH1A1KDM4EMAPT | |
| SCHEMBL25152979 | 0.72 | MAPK1 (0.62) | KMT2ARAB9AMAPK1POLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4837305-A | Derivatives of β-adrenergic antagonists | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1989-06-06 | — | — | US | disclosed |
| US-4687873-A | Derivatives of β-adrenergic antagonists | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1987-08-18 | — | — | US | disclosed |
| EP-0117089-A1 | Beta-adrenergic antagonist compounds and derivatives of beta-adrenergic antagonists | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1984-08-29 | — | — | EP | disclosed |