Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.70 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL772374 | 0.78 | KMT2A (0.69) | KMT2ARAB9ATSHRMEN1MAPK1 | |
| SCHEMBL18527815 | 0.77 | KMT2A (0.72) | KMT2ARAB9AMEN1MAPK1HPGD | |
| SCHEMBL18527818 | 0.77 | KMT2A (0.72) | KMT2ARAB9AMEN1MAPK1HPGD | |
| SCHEMBL11195417 | 0.77 | KMT2A (0.60) | KMT2ARAB9AMEN1GAANTSR1 | |
| SCHEMBL10817898 | 0.77 | KMT2A (0.60) | KMT2ARAB9AMEN1GAANTSR1 | |
| SCHEMBL15293255 | 0.77 | TSHR (0.59) | KMT2ATSHRMEN1GAANTSR1 | |
| SCHEMBL9174228 | 0.77 | KMT2A (0.78) | KMT2ARAB9ATSHRMAPK1HPGD | |
| SCHEMBL10608854 | 0.76 | KMT2A (0.73) | KMT2ARAB9AMAPK1HPGDLMNA | |
| SCHEMBL10603852 | 0.76 | KMT2A (0.70) | KMT2ARAB9ATSHRMEN1GAA | |
| SCHEMBL14948534 | 0.76 | MAPK1 (0.69) | KMT2ARAB9ATSHRMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649402-A1 | PRO-DRUG CAPABLE OF RELEASING AN OXAZOLIDINONE AND, IF NEED BE, AN ACETAMIDOPHENOL | UNIVERSITE PAUL SABATIER (TOULOUSE III) (FR) | 1995-04-26 | — | — | EP | disclosed |
| WO-1994001395-A1 | PRO-DRUG CAPABLE OF RELEASING AN OXAZOLIDINONE AND, IF NEED BE, AN ACETAMIDOPHENOL | UNIVERSITE PAUL SABATIER TOULOUSE III (FR) | 1994-01-20 | — | — | WO | disclosed |