Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | OGG1 | O15527 | 1/20 | 0.56 |
| ▸ | CASP3 | P42574 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.53 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | G6PD | P11413 | 1/20 | 0.49 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | PRNP | P04156 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10722072 | 0.84 | OGG1 (0.58) | ALDH1A1KDM4EHPGDTDP1OGG1 | |
| SCHEMBL8544589 | 0.83 | OGG1 (0.60) | ALDH1A1KDM4EHPGDTDP1OGG1 | |
| SCHEMBL8544596 | 0.83 | OGG1 (0.60) | ALDH1A1KDM4EHPGDTDP1OGG1 | |
| SCHEMBL10609426 | 0.82 | TSHR (0.62) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL10609374 | 0.82 | MEN1 (0.60) | ALDH1A1KDM4EHPGDTDP1MEN1 | |
| SCHEMBL7648460 | 0.81 | C3AR1 (0.53) | ALDH1A1KDM4EHPGDTDP1OGG1 | |
| SCHEMBL7648470 | 0.81 | C3AR1 (0.53) | ALDH1A1KDM4EHPGDTDP1OGG1 | |
| SCHEMBL8547788 | 0.80 | OGG1 (0.62) | ALDH1A1KDM4EHPGDTDP1OGG1 | |
| SCHEMBL8547790 | 0.80 | OGG1 (0.62) | ALDH1A1KDM4EHPGDTDP1OGG1 | |
| SCHEMBL7419603 | 0.78 | CASP3 (0.69) | ALDH1A1KDM4EHPGDTDP1OGG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0207690-B1 | N-SUBSTITUTED GLUTAMIC ACID DERIVATIVE AND PROCESS FOR PRODUCTION AND USE THEREOF | SUNTORY LIMITED (JP) | 1989-12-20 | — | — | EP | disclosed |