Styrene

Styrene

SCHEMBL10606293

C=C(C)C(=O)OCC(F)(F)C(F)(F)F.C=C(C)c1ccccc1.C=Cc1ccccc1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.37
ELANE P08246 1/20 0.36
ALDH1A1 P00352 5/20 0.35
MAPT P10636 2/20 0.35
KMT2A Q03164 3/20 0.34
POLB P06746 2/20 0.33
MEN1 O00255 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
TSHR P16473 1/20 0.33
APEX1 P27695 1/20 0.33
HTT P42858 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
HIF1A Q16665 1/20 0.33
KDM4E B2RXH2 2/20 0.32
LMNA P02545 2/20 0.32
GAA P10253 1/20 0.32
MTNR1A P48039 2/20 0.31
MTNR1B P49286 2/20 0.31
ATM Q13315 1/20 0.30
CA12 O43570 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL21219423 0.94 ALDH1A1 (0.38) MAPK1ELANEALDH1A1MAPTKMT2A
Styrene SCHEMBL22497369 0.83 ALDH1A1 (0.40) MAPK1ELANEALDH1A1MAPTKMT2A
Styrene SCHEMBL190323 0.79 MEN1 (0.42) MAPK1ALDH1A1MAPTKMT2APOLB
Styrene SCHEMBL28227128 0.79 ALDH1A1 (0.36) MAPK1ELANEALDH1A1MAPTKMT2A
Styrene SCHEMBL9460991 0.78 KMT2A (0.42) MAPK1ELANEALDH1A1MAPTKMT2A
Styrene SCHEMBL28335398 0.78 FABP7 (0.35) MAPK1ELANEALDH1A1MAPTKMT2A
Styrene SCHEMBL27544635 0.78 ALDH1A1 (0.46) ELANEALDH1A1MAPTPOLBTSHR
SCHEMBL190324 0.78 CYP2C19 (0.39) MAPK1ELANEALDH1A1MAPTKMT2A
Styrene SCHEMBL8361059 0.76 THRB (0.47) MAPK1ELANEALDH1A1MAPTKMT2A
Styrene SCHEMBL10538469 0.76 ALDH1A1 (0.50) ELANEALDH1A1MAPTPOLBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0183213-B1 THERMOSETTING PREFORM HAVING SUPERIOR TRANSPARENCY AND PROCESS FOR PRODUCING MOLDED ARTICLES FROM SAID PREFORM MITSUBISHI RAYON CO., LTD. (JP) 1989-08-09 EP disclosed