Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.46 |
| ▸ | HTR2A | P28223 | 9/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21630261 | 0.80 | FFAR1 (0.42) | ARHTR2ASLC6A4KCNH2 | |
| SCHEMBL984918 | 0.78 | STK39 (0.44) | ARHTR2ASLC6A4KCNH2 | |
| SCHEMBL985888 | 0.75 | EGFR (0.44) | ARMRGPRX4 | |
| SCHEMBL2329802 | 0.74 | SLC6A4 (0.39) | HTR2ASLC6A4KCNH2 | |
| SCHEMBL1375267 | 0.74 | MAPT (0.42) | HTR2ASLC6A4KCNH2 | |
| SCHEMBL10355072 | 0.73 | PTPRZ1 (0.40) | ARSLC6A4 | |
| SCHEMBL145184 | 0.73 | NOTUM (0.33) | AR | |
| SCHEMBL2333939 | 0.73 | EGFR (0.39) | HTR2ASLC6A4KCNH2MRGPRX4 | |
| SCHEMBL11659532 | 0.73 | HTR2A (0.43) | ARHTR2ASLC6A4KCNH2 | |
| SCHEMBL984802 | 0.72 | SLC6A4 (0.47) | ARHTR2ASLC6A4KCNH2MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0218615-B1 | PROCESS FOR THE MANUFACTURE OF BENZOYL UREA | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1989-07-12 | — | — | EP | claimed |